Gupta Ankur, Lee Vivian S, Chung Yiu-Cho, Babb James S, Simonetti Orlando P
Department of Radiology-MRI, New York University Medical Center, 530 First Avenue, New York, NY 10016, USA.
Radiology. 2004 Dec;233(3):921-6. doi: 10.1148/radiol.2333032004. Epub 2004 Oct 29.
Seventeen patients underwent magnetic resonance (MR) imaging for myocardial viability with a protocol approved by the institutional review board and gave written informed consent. Breath-hold cine inversion-recovery segmented k-space true fast imaging with steady-state precession sequence, referred to as inversion time (TI) mapping, was performed to determine optimal TI for myocardial infarction inversion-recovery imaging. From TI mapping, optimal TI was 180-315 msec 10-15 minutes after administration of 0.15 mmol/kg of gadolinium-based contrast material. At that optimal TI, relative signal intensity of infarcted myocardium compared with uninfarcted myocardium was maximal (mean +/- standard deviation, 297.8% +/- 86.5), whereas signal-to-noise ratio of uninfarcted myocardium was minimal (4.5 +/- 1.2). When applied to conventional myocardial infarction inversion-recovery imaging, optimal TI resulted in nulling of signal intensity of uninfarcted myocardium in all patients and in excellent conspicuity of infarcted myocardium in all nine patients with visible infarction.
17名患者按照机构审查委员会批准的方案接受了用于评估心肌存活性的磁共振（MR）成像检查，并签署了书面知情同意书。采用屏气电影反转恢复分段k空间稳态进动序列（称为反转时间（TI）映射）来确定心肌梗死反转恢复成像的最佳TI。通过TI映射，在静脉注射0.15 mmol/kg钆基对比剂后10 - 15分钟，最佳TI为180 - 315毫秒。在该最佳TI时，梗死心肌与未梗死心肌相比的相对信号强度最大（平均值±标准差，297.8%±86.5），而未梗死心肌的信噪比最小（4.5±1.2）。当应用于传统的心肌梗死反转恢复成像时，最佳TI使所有患者的未梗死心肌信号强度消失，并且在所有9名可见梗死灶的患者中梗死心肌的显示效果极佳。
