Beddermann Christoph, Norman John C., Cooley Denton A.
Cardiovascular Surgical Research Laboratories and the Division of Surgery, Texas Heart Institute of St. Luke's Episcopal and Texas Children's Hospitals, Houston, Texas.
Cardiovasc Dis. 1980 Jun;7(2):214-229.
During 1978, 42 consecutive patients underwent simultaneous aortic valve and ascending aorta replacement in our institution. Seventy-one percent were at low risk despite a high incidence of dissection. Twenty-nine percent were high-risk patients requiring repeat or concomitant cardiac procedures, mostly on an emergency basis. Depending upon the extent of the disease at the aortic root, either of two surgical approaches was used: (1) conventional aortic valve and supracoronary ascending aorta replacement, with or without right coronary artery ostium reimplantation, or (2) insertion of a composite graft containing an aortic valve prosthesis, with reconstruction of both coronary arteries. Preservation of coronary ostia was possible in 85% of the patients, and composite grafts were used in 15%. The conventional method was associated with a higher percentage of survivors. This technique was found to be satisfactory unless severe dilatation or complete destruction of the aortic annulus made composite grafting necessary. The latter technique was associated with fewer re-explorations for postoperative hemorrhage. Both procedures were equally effective, resulting in an operative mortality of 10% in uncomplicated situations. Surgery appeared to offer the only chance of survival for the high-risk group, and half of these patients were salvaged.
1978年期间,我院有42例连续患者接受了主动脉瓣和升主动脉同期置换术。尽管夹层发生率很高,但71%的患者风险较低。29%为高危患者,需要重复或同期进行心脏手术,多数为急诊手术。根据主动脉根部疾病的范围,采用了两种手术方法之一:(1)传统的主动脉瓣和冠状动脉上缘升主动脉置换术,伴或不伴右冠状动脉开口再植入术;或(2)植入含主动脉瓣假体的复合移植物,并重建两支冠状动脉。85%的患者能够保留冠状动脉开口,15%的患者使用了复合移植物。传统方法的存活者比例更高。除非主动脉瓣环严重扩张或完全破坏而需要进行复合移植物植入,否则该技术被认为是令人满意的。后一种技术术后因出血而再次手术的次数较少。两种手术方法同样有效,在无并发症的情况下手术死亡率为10%。手术似乎是高危组唯一的生存机会,这些患者中有一半获救。