核酸双链体中2'-N-（芘-1-基）甲基-2'-氨基-LNA单体之间的链间通讯：完全互补性的方向控制和信号传导
Interstrand communication between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity.
作者信息
Hrdlicka Patrick J, Babu B Ravindra, Sørensen Mads D, Wengel Jesper
机构信息
Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, DK-5230 Odense M, Denmark.
出版信息
Chem Commun (Camb). 2004 Jul 7(13):1478-9. doi: 10.1039/b404446k. Epub 2004 Jun 4.
DOI:10.1039/b404446k
PMID:15216339
Abstract
Very efficient interstrand communication systems in nucleic acid duplexes, based on pyrene excimer formation between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers, demonstrate the versatility of functionalized 2'-amino-LNA monomers for Angstrom-scale chemical engineering.
摘要
基于2'-N-(芘-1-基)甲基-2'-氨基-LNA单体之间芘激基缔合物形成的核酸双链体中非常高效的链间通信系统，证明了功能化2'-氨基-LNA单体在埃级化学工程中的多功能性。
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