Lancaster Kristie J
Department of Nutrition, Food Studies, and Public Health, New York University, 35 W 4th Street, 10th Floor, New York, NY 10012 USA.
Adv Chronic Kidney Dis. 2004 Apr;11(2):217-21. doi: 10.1053/j.arrt.2004.01.007.
Most patients with chronic kidney disease (CKD) also have hypertension. It is critical to control blood pressure in CKD to decrease the risk of negative outcomes. Modification of diet can reduce blood pressure, most notably in people with hypertension and in older adults. Current guidelines recommend reducing sodium intake to less than 2.4 g/day and increasing potassium and calcium intakes. Sodium reduction is supported for CKD patients in general. However, increasing potassium intake should be restricted in patients with glomerular filtration rate (GFR) less than 60 mL/min/1.73 m(2). In addition, because of the high phosphorus levels of many calcium-rich foods such as dairy products, calcium intake also should be limited in this low-GFR population. There is increasing evidence for the association of other nutrients such as omega-3 polyunsaturated fatty acids and vitamin C with blood pressure. Those nutrients are also discussed here.
大多数慢性肾脏病(CKD)患者同时患有高血压。控制CKD患者的血压对于降低不良后果风险至关重要。饮食调整可降低血压,这在高血压患者和老年人中最为显著。当前指南建议将钠摄入量减少至每日2.4克以下,并增加钾和钙的摄入量。一般而言,支持CKD患者减少钠摄入。然而,肾小球滤过率(GFR)低于60 mL/min/1.73 m²的患者应限制钾的摄入量。此外,由于许多富含钙的食物(如乳制品)磷含量高,在这个低GFR人群中钙的摄入量也应受限。越来越多的证据表明,其他营养素如ω-3多不饱和脂肪酸和维生素C与血压有关。本文也将讨论这些营养素。