Tantracheewathorn Taweewong, Lolekha Somsak, Tantracheewathorn Supapan
Department of Pediatrics, Bangkok Metropolitan Administration Medical College and Vajira Hospital, Thailand.
J Med Assoc Thai. 2004 Apr;87(4):438-41.
A 40-day-old male infant presented with fever and non-productive cough for 3 weeks, tachypnea and dyspnea 5 days before admission. The chest radiograph and computed tomographic (CT) scan revealed right lung consolidation with pleural effusion. Pleural tapping showed frank pus that grew Nocardia asteroides. The CT scan of the brain and abdomen were normal. The patient was treated with 15 mg/kg/day of trimethoprim and 75 mg/kg/day of sulfamethoxazole intravenously for 3 weeks and then orally for 6 months with complete recovery. T cell quantitative studies were normal and anti-HIV was non-reactive. A flow cytometric assay with Staphylococcal aureus and phorbol myristate acetate (PMA) as the stimulants showed normal oxidative burst which represented normal intracellular killing. One year after completion of treatment, he was healthy and the chest radiograph was normal.
一名40日龄男婴，发热及干咳3周，入院前5天出现呼吸急促和呼吸困难。胸部X线片及计算机断层扫描（CT）显示右肺实变并伴有胸腔积液。胸腔穿刺抽出脓性液体，培养出星形诺卡菌。脑部及腹部CT扫描正常。患者接受静脉注射三甲氧苄氨嘧啶15mg/（kg·天）及磺胺甲恶唑75mg/（kg·天）治疗3周，随后口服6个月，完全康复。T细胞定量研究正常，抗HIV检测为阴性。以金黄色葡萄球菌和佛波酯（PMA）作为刺激物的流式细胞术检测显示氧化爆发正常，提示细胞内杀伤功能正常。治疗结束1年后，他身体健康，胸部X线片正常。
