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免疫功能低下患者发生的由鼻疽诺卡菌引起的致死性脓胸病例。

A fatal case of empyema thoracis by Nocardia farcinica in an immunocompromised patient.

作者信息

Parande M V, Shinde R S, Mantur B G, Parande A M, Chandrashekhar M R, Aralikatti P S, Palled E

机构信息

Department of Microbiology, Belgaum Institute of Medical Sciences, Belgaum, Karnataka, India.

出版信息

Indian J Med Microbiol. 2010 Oct-Dec;28(4):390-2. doi: 10.4103/0255-0857.71831.

Abstract

Empyema thoracis by Nocardia farcinica infection is uncommon. Here we report a rare and fatal infection in a 27-year-old HIV- seropositive male who presented with cough, expectoration, and breathlessness. Nocardia farcinica was isolated from sputum and pus from the pleural cavity. Confirmation of the isolate and minimum inhibitory concentrations (MIC) for various antibiotics was done at the Aerobic Actinomycetes Reference Laboratory, Centres for Disease Control and Prevention (CDC), Atlanta. Patient was treated with suitable antibiotics and antiretroviral drugs in spite of which he eventually succumbed to the disease.

摘要

马杜拉放线菌感染引起的脓胸并不常见。在此,我们报告一例罕见的致命感染病例,患者为一名27岁的HIV血清阳性男性,表现为咳嗽、咳痰和呼吸困难。从痰液和胸腔脓液中分离出马杜拉放线菌。在亚特兰大疾病控制与预防中心(CDC)的需氧放线菌参考实验室对分离菌株进行了鉴定,并测定了其对各种抗生素的最低抑菌浓度(MIC)。尽管对该患者使用了合适的抗生素和抗逆转录病毒药物进行治疗,但他最终仍死于该疾病。

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