Inoue Satoshi, Asano Makoto, Motoi Yurie, Makino Takashi, Yamada Akio
Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Jpn J Infect Dis. 2004 Jun;57(3):110-2.
Feral raccoons captured in Hokkaido, Japan were examined for the presence of rabies virus neutralizing antibody (VNA). Between 2000 to 2002, 741 serum samples were collected and then subjected to VNA titer determination by rapid fluorescent focus inhibition test (RFFIT). Sera showing RFFIT titers of > or =1:25 have been considered as positive according to previous reports. VNA was detected in none of serum samples from the feral raccoons. The present study provides valuable background information for rabies prevention in Japan. The potential risk of raccoon-derived rabies in the wilderness has been of concern because of the increasing number of feral raccoons originally introduced from rabies-endemic countries. The continuous monitoring of sick and/or dead wild raccoons would help to prevent an epidemic spread of raccoon rabies.
对在日本北海道捕获的野生浣熊进行了狂犬病病毒中和抗体（VNA）检测。在2000年至2002年期间，收集了741份血清样本，然后通过快速荧光灶抑制试验（RFFIT）测定VNA滴度。根据先前的报告，RFFIT滴度≥1:25的血清被视为阳性。在野生浣熊的血清样本中均未检测到VNA。本研究为日本的狂犬病预防提供了有价值的背景信息。由于最初从狂犬病流行国家引入的野生浣熊数量不断增加，野生环境中浣熊源性狂犬病的潜在风险一直受到关注。持续监测生病和/或死亡的野生浣熊将有助于预防浣熊狂犬病的流行传播。
