Choudhury S, Rana M P, Chatterjee T K, Mazumder U K, Gupta M
Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India.
Indian J Exp Biol. 1992 Feb;30(2):140-1.
Antimicrobial activities of mycotoxin MT81 and its acetylated, benzoylated and acetic acid derivatives were determined by zone inhibition method. MT81, acetylated MT81 and acetic acid MT81 exhibited sensitivity (31.25, 62.50, 62.50 micrograms/ml respectively) to all the test bacteria. Benzoylated-MT81 did not exhibit any activity even up to 1000 mcg/ml. MT81, its acetylated and acetic acid derivatives exhibited antifungal activity up to 62.5 micrograms/ml and 125.0 micrograms/ml respectively against test yeasts and other fungi. Benzoylated MT81 also exhibited antifungal activity but the degree was comparatively less.
通过抑菌圈法测定了霉菌毒素MT81及其乙酰化、苯甲酰化和乙酸衍生物的抗菌活性。MT81、乙酰化MT81和乙酸MT81对所有测试细菌均表现出敏感性（分别为31.25、62.50、62.50微克/毫升）。苯甲酰化MT81即使在浓度高达1000微克/毫升时也未表现出任何活性。MT81及其乙酰化和乙酸衍生物分别对测试酵母和其他真菌表现出高达62.5微克/毫升和125.0微克/毫升的抗真菌活性。苯甲酰化MT81也表现出抗真菌活性，但程度相对较低。
