Tamura Shigeyuki, Miki Hirofumi, Kittaka Nobuyoshi, Nakata Ken, Kim Chiwan, Takiuchi Daisuke, Okada Kaoru, Okamura Syu, Aihara Tomohiko, Sugimoto Keishi, Ohzato Hiroki, Tomita Naohiro, Takatsuka Yuuichi
Dept. of Surgery, Kansai Rousai Hospital.
Gan To Kagaku Ryoho. 2006 Feb;33(2):243-6.
for over 3 years. A 67-year-old woman underwent distal gastrectomy for advanced gastric cancer. Histological examination of several nodules in the posterior gastric wall led to suspicion of peritoneal dissemination. Low-dose FP treatment was performed for only 5 days after surgery. Peritoneal dissemination was diagnosed at the time of surgery for postoperative abdominal hernia 20 months after the gastrectomy. TS-1 was administered postoperatively, and recurrence or progression has not been detected for 3 years 4 months. Another patient, a 68-year-old woman,underwent distal gastrectomy for advanced gastric cancer with multiple lymph node metastasis and peritoneal dissemination. TS-1 was administered after surgery, and no recurrence or progression has been detected for 3 years and 7 months. These cases suggest that TS-1 is a promising treatment for gastric cancer with peritoneal dissemination.
三年多来，一名67岁女性因晚期胃癌接受了远端胃切除术。对胃后壁多个结节进行组织学检查后怀疑有腹膜播散。术后仅进行了5天的低剂量氟尿嘧啶（FP）治疗。在胃切除术后20个月进行术后腹疝手术时诊断为腹膜播散。术后给予替吉奥（TS-1），3年4个月来未检测到复发或进展。另一名患者，一名68岁女性，因晚期胃癌伴多发淋巴结转移和腹膜播散接受了远端胃切除术。术后给予TS-1，3年7个月来未检测到复发或进展。这些病例表明，TS-1是治疗腹膜播散性胃癌的一种有前景的治疗方法。
