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特发性嗜酸性粒细胞增多综合征的二尖瓣修复术

Mitral valve repair in idiopathic hypereosinophilic syndrome.

作者信息

Fuzellier Jean-François, Chapoutot Laurent, Torossian Pierre-Frederic

机构信息

Department of Cardiothoracic Surgery, Hôpital Robert Debré, Avenue du général Koenig, 51100 Reims, France.

出版信息

J Heart Valve Dis. 2004 May;13(3):529-31.

Abstract

Idiopathic hypereosinophilic syndrome is a rare systemic disease than can cause multiple organ failure by eosinophilic infiltration. Cardiac involvement is characterized by endocardial fibrosis and overlying thrombus, leading to restrictive cardiomyopathy and valvular dysfunction. Surgical experience of patients with mitral dysfunction caused by this syndrome is limited, and valvular replacement is most often performed. Mechanical valvular replacement has a high incidence of recurrent obstructive thrombosis, and replacement with a bioprosthesis is recommended, despite associated restrictive cardiomyopathy. A patient is described who presented with mitral insufficiency associated with idiopathic hypereosinophilic syndrome, and underwent mitral valve repair.

摘要

特发性嗜酸性粒细胞增多综合征是一种罕见的全身性疾病,可通过嗜酸性粒细胞浸润导致多器官衰竭。心脏受累的特征是心内膜纤维化和覆盖其上的血栓,导致限制性心肌病和瓣膜功能障碍。该综合征所致二尖瓣功能障碍患者的手术经验有限,最常进行瓣膜置换。机械瓣膜置换术后复发性梗阻性血栓形成的发生率很高,尽管存在相关的限制性心肌病,但仍建议使用生物假体进行置换。本文描述了一名患有特发性嗜酸性粒细胞增多综合征相关二尖瓣关闭不全并接受二尖瓣修复术的患者。

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