Parsons Brad, Strauss Elton
Department of Orthopaedics, Mount Sinai Medical Center, 5 East 98th Street, Box 1188, New York, NY 10029, USA.
Am J Surg. 2004 Jul;188(1A Suppl):57-66. doi: 10.1016/S0002-9610(03)00292-7.
Chronic osteomyelitis is a surgical disease that can require significant dedication from both patients and surgeons to eradicate. Osteomyelitis can result from a variety of etiologies but most often is a consequence of trauma to a long bone, frequently the tibia. It is important to understand the etiology of the infection, as well as the pathophysiology of its chronicity. Additionally, the surgeon must individualize treatment for each patient, because host morbidities often play an important role in propagation of infection. Treatment requires isolation of the pathogens, significant debridement for removal of all infective and necrotic material, and then bony and soft tissue reconstruction. We review the literature of surgical treatment of chronic osteomyelitis and discuss the numerous techniques available to the treatment team, including debridement, dead space management, Ilizarov techniques, and vascularized reconstruction. These patients often require a multimodality approach that incorporates a team approach involving orthopedic and plastic surgery, as well as infectious disease and general medicine.
慢性骨髓炎是一种外科疾病,需要患者和外科医生付出巨大努力才能根除。骨髓炎可由多种病因引起,但最常见的是长骨(通常是胫骨)创伤的结果。了解感染的病因以及其慢性化的病理生理学很重要。此外,外科医生必须为每个患者制定个性化的治疗方案,因为宿主的发病率往往在感染的传播中起重要作用。治疗需要分离病原体,进行大量清创以清除所有感染性和坏死物质,然后进行骨和软组织重建。我们回顾了慢性骨髓炎外科治疗的文献,并讨论了治疗团队可用的众多技术,包括清创、死腔管理、伊利扎洛夫技术和血管化重建。这些患者通常需要多模式治疗方法,包括由骨科和整形外科以及传染病和普通内科组成的团队治疗方法。