Bamberger D M
Section of Infectious Diseases, University of Missouri-Kansas City School of Medicine.
Postgrad Med. 1993 Oct;94(5):177-82, 184.
Therapy for osteomyelitis requires a multidisciplinary approach. A precise microbiologic diagnosis and adequate debridement of necrotic tissue are essential. Acute hematogenous osteomyelitis usually responds to antimicrobial therapy. The presence of an abscess or a metaphyseal cavity in hematogenous osteomyelitis and evidence of spinal cord compression in vertebral osteomyelitis require surgical treatment. Chronic osteomyelitis usually implies that dead bone is present, which requires surgical debridement. Because of the chronicity of the infection and various presentations and surgical approaches, antibiotic treatment must be individualized. In general, however, at least 4 weeks of therapy is required.
骨髓炎的治疗需要多学科方法。精确的微生物学诊断和对坏死组织进行充分清创至关重要。急性血源性骨髓炎通常对抗菌治疗有反应。血源性骨髓炎中存在脓肿或干骺端腔以及脊椎骨髓炎中有脊髓受压的证据则需要手术治疗。慢性骨髓炎通常意味着存在死骨，这需要手术清创。由于感染的慢性性质、各种表现及手术方式，抗生素治疗必须个体化。然而，一般来说，至少需要4周的治疗。
