Thalhammer C, Aschwanden M, Jeanneret C, Labs K H, Jäger K A
Department of Angiology, University Hospital, Kantonsspital, Basel, Switzerland.
Vasa. 2004 May;33(2):78-81. doi: 10.1024/0301-1526.33.2.78.
Haemostatic puncture closure devices for rapid and effective hemostasis after arterial catheterisation are a comfortable alternative to manual compression. Implanting a collagen plug against the vessel wall may become responsible for other kind of vascular injuries i.e. thrombotic or stenotic lesions and peripheral embolisation. The aim of this paper is to report our clinically relevant vascular complications after Angio-Seal and to discuss the results in the light of the current literature.
We report the symptomatic vascular complications in 17 of 7376 patients undergoing diagnostic or therapeutic catheterisation between May 2000 and March 2003 at the University Hospital Basel.
Most patients presented with ischaemic symptoms, arterial stenoses or occlusions and thrombotic lesions (n = 14), whereas pseudoaneurysms were extremely rare (n = 3). Most patients with ischaemic lesions underwent vascular surgery and all patients with a pseudoaneurysm were successfully treated by ultrasound-guided compression.
Severe vascular complications after Angio-Seal are rare, consistent with the current literature. There may be a shift from pseudoaneurysms to ischaemic lesions.
动脉导管插入术后用于快速有效止血的止血穿刺闭合装置是手动压迫的一种舒适替代方法。在血管壁植入胶原蛋白栓可能会导致其他类型的血管损伤，如血栓形成或狭窄性病变以及外周栓塞。本文旨在报告我们在使用血管封堵器（Angio-Seal）后临床上相关的血管并发症，并根据当前文献讨论结果。
我们报告了2000年5月至2003年3月在巴塞尔大学医院接受诊断性或治疗性导管插入术的7376例患者中17例出现症状性血管并发症的情况。
大多数患者表现为缺血症状、动脉狭窄或闭塞以及血栓形成病变（n = 14），而假性动脉瘤极为罕见（n = 3）。大多数有缺血性病变的患者接受了血管手术，所有假性动脉瘤患者均通过超声引导压迫成功治疗。
血管封堵器（Angio-Seal）术后严重血管并发症罕见，与当前文献一致。可能存在从假性动脉瘤向缺血性病变的转变。
