Smets Koenraad, Zecic Alexandra, Willems Jef
Neonatal Intensive Care Unit, Ghent University Hospital, Ghent, Belgium.
J Child Neurol. 2004 May;19(5):398. doi: 10.1177/088307380401900518.
A case of Möbius sequence after exposure to ergotamine during early development is reported. Vascular disruption is one of the theories explaining the pathogenesis of Möbius sequence. Ergotamine can cause vasospasm and a prolonged and marked increase in uterine tone. This is the second report suggesting a relation between maternal ingestion of ergotamine in early pregnancy and subsequent Möbius sequence in a child.
报道了一例在早期发育过程中接触麦角胺后出现默比厄斯序列的病例。血管破坏是解释默比厄斯序列发病机制的理论之一。麦角胺可引起血管痉挛以及子宫张力长时间显著增加。这是第二份表明孕妇在孕早期摄入麦角胺与孩子随后出现默比厄斯序列之间存在关联的报告。
