Ipp Moshe, Taddio Anna, Goldbach Morton, Ben David Shlomit, Stevens Bonnie, Koren Gideon
Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada.
Can J Clin Pharmacol. 2004 Spring;11(1):e2-7. Epub 2004 Apr 1.
Determinants of infant pain responses are important when assessing the efficacy of analgesics. In a randomized controlled trial, 106 infants aged 2 to 6 months were positioned either supine (SUP) on the examination table or held (HLD) by a parent during routine immunization in a community pediatric office. There was no difference between the SUP and HLD infants in duration of crying, facial grimacing or visual analogue scale (VAS) pain scores. Similarly gender did not affect pain response. In contrast, 2-month-old infants displayed more pain during immunization than did 4 or 6-month-old infants.
在评估镇痛药疗效时,婴儿疼痛反应的决定因素很重要。在一项随机对照试验中,106名2至6个月大的婴儿在社区儿科诊所进行常规免疫接种时,要么仰卧(SUP)在检查台上,要么由父母抱着(HLD)。仰卧和被抱着的婴儿在哭闹持续时间、面部 grimacing 或视觉模拟量表(VAS)疼痛评分方面没有差异。同样,性别也不影响疼痛反应。相比之下,2个月大的婴儿在免疫接种期间比4或6个月大的婴儿表现出更多疼痛。