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德克萨斯心脏研究所对三名患者进行了异位心脏移植。

Heterotopic heart transplantation in three patients at the Texas Heart Institute.

作者信息

Frazier O H, Okereke J, Cooley D A, Radovancevic B, Chandler L B, Powers P

机构信息

Division of Surgery and the Transplantation Unit, Texas Heart Institute and St. Luke's Episcopal Hospital, Houston, Texas 77225, USA.

出版信息

Tex Heart Inst J. 1985 Sep;12(3):221-32.

Abstract

Seventy-three orthotopic and three heterotopic transplantations have been done in our institution, and in this report, we describe the procedure and outcome of those who underwent heterotopic transplantation. Three patients were in critical condition while awaiting donors for heart transplantation, and in each case, a suitable donor could not be found. Smaller donor hearts became available, and knowing that these patients would die without some kind of immediate action, we performed heterotopic heart transplantations. Patient Number 1 was a 53-year-old diabetic man who was in the last stages of heart disease when a small donor heart became available. Because of his rapidly deteriorating condition, we did a heterotopic transplantation. The patient is presently well and functioning normally. Patient Number 2 was a 26-year-old woman who received the heart of a 13-year-old donor after it became obvious that she could not wait for a suitable donor. We performed a heterotopic transplantation, after which the patient continues to function well. Patient Number 3 was a 53-year-old man who weighed 260 lbs. When a suitable donor could not be found, the heart of a 170-lb man became available and was used in a heterotopic transplantation. This patient also continues to be active and well. After considering the various advantages and disadvantages of heterotopic transplantation, we are convinced that there is a definite place for this procedure in some patients with end-stage cardiac failure, although we still believe that orthotopic transplantation should be offered to most recipients.

摘要

我们机构已进行了73例原位移植和3例异位移植,在本报告中,我们描述了接受异位移植患者的手术过程及结果。3例患者在等待心脏移植供体时病情危急,且每例均未找到合适的供体。有较小的供体心脏可供使用,鉴于这些患者若不立即采取措施将会死亡,我们实施了异位心脏移植。1号患者是一名53岁的糖尿病男性,在出现较小的供体心脏时已处于心脏病晚期。由于其病情迅速恶化,我们进行了异位移植。该患者目前情况良好,功能正常。2号患者是一名26岁的女性,在明显无法等待合适供体后,接受了一名13岁供体的心脏。我们进行了异位移植,术后该患者功能持续良好。3号患者是一名体重260磅的53岁男性。当未找到合适供体时,一名体重170磅男性的心脏可供使用,并用于异位移植。该患者也一直很活跃,情况良好。在考虑了异位移植的各种优缺点后,我们确信,对于一些终末期心力衰竭患者,该手术有其明确的应用价值,尽管我们仍然认为大多数受者应接受原位移植。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/830e/341860/2303faadfbbe/thij00003-0023-a.jpg

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