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在严重急性排斥反应的治疗中,异位心脏移植相对于原位心脏移植的优势。

The advantage of heterotopic cardiac transplantation over orthotopic cardiac transplantation in the management of severe acute rejection.

作者信息

Barnard C N, Losman J G, Curcio C A, Sanchez H E, Wolpowitz A, Barnard M S

出版信息

J Thorac Cardiovasc Surg. 1977 Dec;74(6):918-24.

PMID:336984
Abstract

The major problems with organ transplantation are rejection of the allograft and the side effects of antirejection therapy. This report describes the successful treatment of a patient in whom rejection of the donor heart developed 10 months after implantation. The recipient's own heart had been left intact and was able to support the circulation during the period of rejection. Indications are that the "rest" period of 10 months was beneficial to the myopathic left ventricle of the recipient's heart.

摘要

器官移植的主要问题是同种异体移植物的排斥反应以及抗排斥治疗的副作用。本报告描述了一名患者的成功治疗案例,该患者在心脏植入10个月后出现供体心脏排斥反应。受体自身的心脏保持完好,并在排斥反应期间能够维持血液循环。有迹象表明,10个月的“休息”期对受体心脏的肌病性左心室有益。

相似文献

1
The advantage of heterotopic cardiac transplantation over orthotopic cardiac transplantation in the management of severe acute rejection.在严重急性排斥反应的治疗中,异位心脏移植相对于原位心脏移植的优势。
J Thorac Cardiovasc Surg. 1977 Dec;74(6):918-24.
2
Orthotopic and heterotopic transplantation of the heart: the Cape Town experience.心脏的原位和异位移植:开普敦的经验。
Ann R Coll Surg Engl. 1984 Jul;66(4):228-34.
3
Changes in indications for heart transplantation. An additional argument for the preservation of the recipient's own heart.心脏移植适应证的变化。保留受者自身心脏的另一个理由。
J Thorac Cardiovasc Surg. 1982 Nov;84(5):716-26.
4
Late acute cardiac allograft rejection: new therapeutic options?晚期急性心脏移植排斥反应:新的治疗选择?
Transplant Proc. 2005 Dec;37(10):4528-31. doi: 10.1016/j.transproceed.2005.11.053.
5
Ventricular fibrillation during acute rejection after heart transplantation.心脏移植后急性排斥反应期间的心室颤动。
J Heart Lung Transplant. 1992 Jul-Aug;11(4 Pt 1):797-8.
6
The value of recipient heart assistance during severe acute rejection following heterotopic cardiac transplantation.
J Cardiovasc Surg (Torino). 1984 Jul-Aug;25(4):287-95.
7
Sequentially paced heterotopic heart transplant in the left chest provides improved circulatory support for the failed left ventricle. A potential biologic bridge to orthotopic transplantation.左胸序贯式异位心脏移植可为衰竭的左心室提供更好的循环支持。这是一种原位移植潜在的生物桥梁。
J Thorac Cardiovasc Surg. 1989 Aug;98(2):266-74.
8
Intermediate term results of infant orthotopic cardiac transplantation from two centers.两个中心婴儿原位心脏移植的中期结果。
J Thorac Cardiovasc Surg. 1991 May;101(5):826-32.
9
Effects of methotrexate on acute rejection and cardiac allograft vasculopathy in heart transplant recipients.甲氨蝶呤对心脏移植受者急性排斥反应和心脏移植血管病变的影响。
J Heart Lung Transplant. 1997 Feb;16(2):169-78.
10
Hemodynamic observations following orthotopic cardiac transplantation: evolution of rest hemodynamics in the first year.原位心脏移植后的血流动力学观察:第一年静息血流动力学的演变
Acta Physiol Hung. 1992;79(1):57-64.

引用本文的文献

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Hemodynamics in pig-to-baboon heterotopic thoracic cardiac xenotransplantation: Recovery from perioperative cardiac xenograft dysfunction and impairment by cardiac overgrowth.猪到狒狒异位胸腔心脏异种移植中的血液动力学:心脏异种移植物功能障碍和心脏过度生长导致的围手术期损害的恢复。
Xenotransplantation. 2024 Jan-Feb;31(1):e12841. doi: 10.1111/xen.12841.
2
Cardiac xenotransplantation: from concept to clinic.心脏异种移植:从概念到临床。
Cardiovasc Res. 2023 Feb 3;118(18):3499-3516. doi: 10.1093/cvr/cvac180.
3
Progress Toward Cardiac Xenotransplantation.
迈向心脏异种移植的进展。
Circulation. 2020 Oct 6;142(14):1389-1398. doi: 10.1161/CIRCULATIONAHA.120.048186. Epub 2020 Oct 5.
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Current status of pig heart xenotransplantation.猪心脏异种移植的现状。
Int J Surg. 2015 Nov;23(Pt B):234-239. doi: 10.1016/j.ijsu.2015.08.038. Epub 2015 Aug 28.
5
Heterotopic heart transplantation: current indications for the procedure, with results in 10 patients.异位心脏移植:该手术的当前适应症及10例患者的结果
Tex Heart Inst J. 1988;15(3):159-62.
6
Heterotopic heart transplantation in three patients at the Texas Heart Institute.德克萨斯心脏研究所对三名患者进行了异位心脏移植。
Tex Heart Inst J. 1985 Sep;12(3):221-32.
7
Long-term survival after orthotopic and heterotopic cardiac transplantation.原位和异位心脏移植后的长期存活情况。
Br Med J. 1980 Oct 25;281(6248):1093-6. doi: 10.1136/bmj.281.6248.1093.
8
Radiographic findings in the chest of patients following cardiac transplantation.
Cardiovasc Intervent Radiol. 1983;6(1):1-6. doi: 10.1007/BF02552785.