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成人下呼吸道感染与社区获得性肺炎

Lower respiratory tract infections and community acquired pneumonia in adults.

作者信息

Stocks Nigel, Turnidge John, Crockett Alan

机构信息

Department of General Practice, University of Adelaide, South Australia.

出版信息

Aust Fam Physician. 2004 May;33(5):297-301.

Abstract

BACKGROUND

Lower respiratory tract infections--acute bronchitis and community acquired pneumonia (CAP)--are important causes of morbidity in Australia. Acute bronchitis is often treated with antibiotics, although the cause is usually viral. Community acquired pneumonia may be fatal, particularly in the elderly, therefore appropriate assessment and management is essential.

OBJECTIVE

This article describes the aetiology, clinical assessment, investigations and management of acute bronchitis and CAP in the community.

DISCUSSION

Clinical assessment is important for acute bronchitis and CAP, with investigations such as C reactive protein, serology, and chest X-ray informing diagnosis and management of the latter. Causative organisms are usually not identified, but are presumed to be viral for acute bronchitis, and Streptococcus pneumoniae for CAP; although 'atypicals' are also important. Antibiotics should generally not be prescribed for acute bronchitis, however, there is some evidence they may provide limited benefits in patients who have chest signs, are very unwell, are older, have comorbidities, or smoke. In patients with CAP, treated outside of hospital, the combination of amoxycillin and doxycycline/roxithromycin is the treatment of choice.

摘要

背景

下呼吸道感染——急性支气管炎和社区获得性肺炎(CAP)——是澳大利亚发病的重要原因。急性支气管炎通常用抗生素治疗,尽管病因通常是病毒性的。社区获得性肺炎可能是致命的,尤其是在老年人中,因此进行适当的评估和管理至关重要。

目的

本文描述了社区中急性支气管炎和CAP的病因、临床评估、检查及管理。

讨论

临床评估对急性支气管炎和CAP很重要,诸如C反应蛋白、血清学及胸部X光等检查有助于后者的诊断和管理。致病微生物通常无法确定,但推测急性支气管炎的病因是病毒,CAP的病因是肺炎链球菌;尽管“非典型病原体”也很重要。一般不应为急性支气管炎开抗生素,然而,有一些证据表明,抗生素可能对有胸部体征、病情非常严重、年龄较大、有合并症或吸烟的患者有有限益处。对于在院外治疗的CAP患者,阿莫西林与多西环素/罗红霉素联合使用是首选治疗方法。

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