灭活布鲁氏菌对免疫反应的调节作用：光滑型菌株与粗糙型菌株对T细胞依赖性反应影响的比较
Modulation of immune response by killed Brucella abortus organisms: comparison of the effects of smooth and rough strains on T-dependent responses.
作者信息
Martin A, Le Garrec Y, Dazord L, Toujas L
出版信息
Infect Immun. 1978 Sep;21(3):1027-8. doi: 10.1128/iai.21.3.1027-1028.1978.
Abstract
Inactivated Brucella abortus organisms of the smooth (S) or rough (R) strain were tested comparatively on two T-dependent immune responses: mixed-lymphocyte reaction and delayed-type hypersensitivity. The intravenous injection of S organisms depressed the two tests, whereas R organisms increased mixed-lymphocyte reaction and did not alter delayed-type hypersensitivity significantly. This observation may be helpful in understanding the differences in adjuvant properties of S and R brucellae.
摘要
对光滑（S）株或粗糙（R）株的灭活布鲁氏菌流产杆菌在两种T细胞依赖性免疫反应中进行了比较测试：混合淋巴细胞反应和迟发型超敏反应。静脉注射S株细菌会抑制这两种测试，而R株细菌则增强了混合淋巴细胞反应，并且对迟发型超敏反应没有显著影响。这一观察结果可能有助于理解S型和R型布鲁氏菌在佐剂特性方面的差异。
相似文献
1
Modulation of immune response by killed Brucella abortus organisms: comparison of the effects of smooth and rough strains on T-dependent responses.灭活布鲁氏菌对免疫反应的调节作用：光滑型菌株与粗糙型菌株对T细胞依赖性反应影响的比较
Infect Immun. 1978 Sep;21(3):1027-8. doi: 10.1128/iai.21.3.1027-1028.1978.
2
The effects of adjuvants on immune responses in cattle injected with a Brucella abortus soluble antigen.佐剂对注射布鲁氏菌流产亚种可溶性抗原的牛免疫反应的影响。
Vet Microbiol. 1991 Sep;29(1):27-48. doi: 10.1016/0378-1135(91)90108-r.
3
Comparative immune responses to native cell envelope antigens and the hot sodium dodecyl sulfate insoluble fraction (PG) of Brucella abortus in cattle and mice.牛和小鼠对流产布鲁氏菌天然细胞包膜抗原及热十二烷基硫酸钠不溶组分（PG）的免疫反应比较
Vet Immunol Immunopathol. 1988 Mar;18(2):149-63. doi: 10.1016/0165-2427(88)90057-8.
4
Antibody response, delayed hypersensitivity, and immunity in guinea pigs induced by smooth and rough strains of Brucella abortus.流产布鲁氏菌光滑型菌株和粗糙型菌株诱导豚鼠产生的抗体反应、迟发型超敏反应及免疫
J Infect Dis. 1971 Jul;124(1):47-57. doi: 10.1093/infdis/124.1.47.
5
Resistance to tumor graft in mice treated with inactivated Brucella abortus cultured in smooth or rough phase.用在光滑或粗糙阶段培养的灭活布鲁氏菌流产株处理的小鼠对肿瘤移植的抵抗力。
J Natl Cancer Inst. 1979 Jan;62(1):123-7.
6
Recombinant Brucella abortus proteins that induce proliferation and gamma-interferon secretion by CD4+ T cells from Brucella-vaccinated mice and delayed-type hypersensitivity in sensitized guinea pigs.重组流产布鲁氏菌蛋白，可诱导接种布鲁氏菌的小鼠的CD4 + T细胞增殖和γ-干扰素分泌，并在致敏豚鼠中引发迟发型超敏反应。
Cell Immunol. 1996 Sep 15;172(2):262-8. doi: 10.1006/cimm.1996.0241.
7
Immunopotentiation of cattle vaccinated with a soluble Brucella abortus antigen with low LPS content: an analysis of cellular and humoral immune responses.用低脂多糖含量的可溶性流产布鲁氏菌抗原对牛进行免疫增强：细胞免疫和体液免疫反应分析
Vet Microbiol. 1991 Sep;29(1):15-26. doi: 10.1016/0378-1135(91)90107-q.
8
9
A comparison of the potency of several Brucella allergens used to detect brucellosis in cattle.几种用于检测牛布鲁氏菌病的布鲁氏菌变应原效力的比较。
Vet Res Commun. 1996;20(2):141-51. doi: 10.1007/BF00385635.
10
Comparison of Brucella abortus antigen preparations for in vitro stimulation of immune bovine T-lymphocyte cell lines.用于体外刺激免疫牛T淋巴细胞系的流产布鲁氏菌抗原制剂的比较
Vet Immunol Immunopathol. 1993 Feb;36(1):45-64. doi: 10.1016/0165-2427(93)90005-o.
引用本文的文献
1
A 36-kilodalton Brucella abortus cell envelope protein is encoded by repeated sequences closely linked in the genomic DNA.一种36千道尔顿的流产布鲁氏菌细胞包膜蛋白由基因组DNA中紧密相连的重复序列编码。
Infect Immun. 1988 Aug;56(8):2036-46. doi: 10.1128/iai.56.8.2036-2046.1988.
本文引用的文献
1
[ADJUVANT PROPERTIES OF CORYNEBACTERIUM PARVUM ON ANTIBODY PRODUCTION AND ON THE INDUCTION OF DELAYED HYPERSENSITIVITY TOWARD CONJUGATED PROTEINS].短小棒状杆菌对抗体产生及对结合蛋白迟发型超敏反应诱导的佐剂特性
Ann Inst Pasteur (Paris). 1964 May;106:771-7.
2
The mechanism of immunostimulation induced by inactivated Brucella abortus.灭活布鲁氏菌诱导免疫刺激的机制。
Rev Eur Etud Clin Biol. 1972 Mar;17(3):267-73.
3
Immunopotentiation with BCG. II. Modulation of the response to sheep red blood cells.卡介苗免疫增强作用。II. 对绵羊红细胞反应的调节
J Natl Cancer Inst. 1973 Nov;51(5):1669-76. doi: 10.1093/jnci/51.5.1669.
4
Biological effects of the adjuvant Corynebacterium parvum. I. Inhibition of PHA, mixed lymphocyte and GVH reactivity.佐剂短小棒状杆菌的生物学效应。I. 对PHA、混合淋巴细胞反应及移植物抗宿主反应的抑制作用
Cell Immunol. 1972 Nov;5(3):459-68. doi: 10.1016/0008-8749(72)90072-x.
5
6
7
Influence of the antigenicity of Brucella preparations on modulation of the immune response to sheep erythrocytes.布鲁氏菌制剂的抗原性对绵羊红细胞免疫反应调节的影响。
Infect Immun. 1978 Apr;20(1):6-11. doi: 10.1128/iai.20.1.6-11.1978.
Zotero 插件