甲状腺岛叶癌伴颈静脉侵犯。
Insular carcinoma of the thyroid with jugular vein invasion.
作者信息
Leong Jern-Lin, Yuen Heng Wai, LiVolsi Virginia A, Loevner Laurie, Narula Navneet, Baloch Zubair, Weber Randal S
机构信息
Department of Otolaryngology, National University Hospital, Republic of Singapore.
出版信息
Head Neck. 2004 Jul;26(7):642-6. doi: 10.1002/hed.20037.
BACKGROUND
Gross angioinvasion with intraluminal tumor thrombus is rarely seen in thyroid cancer, with few cases reported in the literature.
METHODS
We report an insular carcinoma of the thyroid displaying this aggressive local invasion and angioinvasion of the internal jugular chain. Complete surgical removal of the intraluminal disease, regional metastasis, and primary tumor was carried out.
RESULTS
Adjuvant external beam radiation therapy and iodine-131 were administered, and the patient died with pulmonary metastases 30 months after surgery. No locoregional recurrence was noted at last follow-up.
CONCLUSIONS
Treatment of insular carcinoma of the thyroid with invasion of the internal jugular vein is amenable to surgical resection. Postoperative radioactive iodine and external beam radiotherapy can achieve locoregional disease control and prolonged survival.
背景
甲状腺癌中出现伴有腔内肿瘤血栓的大体血管侵犯情况极为罕见，文献报道的病例很少。
方法
我们报告了1例甲状腺岛状癌，其表现出这种侵袭性局部侵犯及颈内链血管侵犯。对腔内病变、区域转移灶及原发肿瘤进行了完整的手术切除。
结果
给予辅助外照射放疗及碘-131治疗，患者术后30个月死于肺转移。最后一次随访时未发现局部区域复发。
结论
伴有颈内静脉侵犯的甲状腺岛状癌可通过手术切除进行治疗。术后放射性碘及外照射放疗可实现局部区域疾病控制并延长生存期。
Zotero 插件