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纤维肌痛女性的医疗服务成本及其决定因素。

Health services costs and their determinants in women with fibromyalgia.

作者信息

Penrod John R, Bernatsky Sasha, Adam Viviane, Baron Murray, Dayan Natalie, Dobkin Patricia L

机构信息

Division of Clinical Epidemiology, Department of Medicine, McGill University Health Centre, Quebec, Canada.

出版信息

J Rheumatol. 2004 Jul;31(7):1391-8.

Abstract

OBJECTIVE

Patients with fibromyalgia (FM) use health services extensively. Knowledge about costs of FM is limited because of non-inclusiveness in assessing direct costs, because attempts to assess indirect costs are largely absent, and because determinants of costs have yet to be identified. We investigated the 6-month costs (direct and indirect) in women with primary FM, and we identified determinants of direct costs.

METHODS

Subjects (n = 180 women) completed a health resource questionnaire as well as measures of pain, psychological distress, comorbidity, and disability. Unit costs for resources were obtained from government, hospital, laboratory, and professional association sources. Regression modeling for 6-month direct cost included age, disability, comorbidity, pain intensity, psychological distress, education, and work status.

RESULTS

The average 6-month direct cost was $CDN 2298 (SD 2303). The largest components were medications ($CDN 758; SD 654), complementary and alternative medicine (CAM; $CDN 398; SD 776), and diagnostic tests ($CDN 356; SD 580). Our most conservative estimate of average 6-month indirect cost was $CDN 5035 (SD 7439). Comorbidity and FM disability were statistically significant contributors to direct costs in the multivariate analysis. Costs increased by approximately 20% with each additional comorbid condition.

CONCLUSION

Women with FM are high consumers of both conventional and CAM services. Our estimates of costs exceed those from most other studies; this may be due to our inclusion of a broader set of health services, medications, and indirect costs. Although in univariate analyses the number of comorbidities and indices of the effect of FM, psychological distress, and pain intensity were associated with higher direct cost, in a multiple regression analysis, only the measure of FM disability and the number of comorbidities were significant direct-cost determinants. FM also imposes important indirect costs, which were nearly 70% of the economic burden.

摘要

目的

纤维肌痛(FM)患者广泛使用医疗服务。由于在评估直接成本时未涵盖所有方面、在评估间接成本方面的尝试基本缺失以及成本的决定因素尚未确定,关于FM成本的了解有限。我们调查了原发性FM女性患者6个月的成本(直接成本和间接成本),并确定了直接成本的决定因素。

方法

受试者(n = 180名女性)完成了一份健康资源问卷以及疼痛、心理困扰、合并症和残疾的测量。资源的单位成本来自政府、医院、实验室和专业协会。6个月直接成本的回归模型包括年龄、残疾、合并症、疼痛强度、心理困扰、教育程度和工作状态。

结果

6个月的平均直接成本为2298加元(标准差2303)。最大的组成部分是药物(758加元;标准差654)、补充和替代医学(CAM;398加元;标准差776)以及诊断测试(356加元;标准差580)。我们对6个月间接成本的最保守估计为5035加元(标准差7439)。在多变量分析中,合并症和FM残疾是直接成本的统计学显著贡献因素。每增加一种合并症,成本大约增加20%。

结论

FM女性患者是传统和CAM服务的高消费者。我们估计的成本超过了大多数其他研究;这可能是由于我们纳入了更广泛的一系列医疗服务、药物和间接成本。尽管在单变量分析中,合并症的数量以及FM、心理困扰和疼痛强度的影响指数与更高的直接成本相关,但在多元回归分析中,只有FM残疾测量和合并症数量是显著的直接成本决定因素。FM还带来了重要的间接成本,几乎占经济负担的70%。

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