Suppr超能文献

纤维肌痛发作的特征:一项前瞻性观察研究。

Characterizing fibromyalgia flares: a prospective observational study.

作者信息

Gomez-Arguelles Jose Maria, Moreno-Zazo Marco, Maestu Ceferino

机构信息

Department of Neurology, Quiron University Hospital, Madrid, Spain.

Centre of Biomedical Technology/CiberBNN, Polytechnic University of Madrid, Madrid, Spain.

出版信息

Reumatologia. 2022;60(4):242-246. doi: 10.5114/reum.2022.118677. Epub 2022 Sep 7.

Abstract

INTRODUCTION

Although most patients with fibromyalgia describe periods of exacerbation of their symptomatology, there are very few studies describing its characteristics.

MATERIAL AND METHODS

We recruited a total of 124 patients from our outpatient clinics who agreed to a follow-up of at least 6 months. All of them were asked to note and describe whether they had had any worsening of their symptoms during that time.

RESULTS

Sixty-nine patients (75%) reported at least one flare, with a mean of 2 flares per patient. The mean duration of flares was 11 weeks. The most frequent triggers were: continuous stress (56%), intense stress (39%), physical overexertion (37%) and climatic changes (36%). The most common actions taken by patients were rest and medication.

CONCLUSIONS

Two-thirds of fibromyalgia patients experienced flares within 6 months. The symptoms and measures taken are similar to those patients usually take when they notice a worsening of symptoms.

摘要

引言

尽管大多数纤维肌痛患者描述其症状有加重期,但很少有研究描述其特征。

材料与方法

我们从门诊招募了总共124名同意至少随访6个月的患者。要求他们所有人记录并描述在此期间症状是否有任何恶化。

结果

69名患者(75%)报告至少有一次病情发作,每位患者平均发作2次。发作的平均持续时间为11周。最常见的诱因是:持续压力(56%)、强烈压力(39%)、身体过度劳累(37%)和气候变化(36%)。患者采取的最常见行动是休息和用药。

结论

三分之二的纤维肌痛患者在6个月内经历病情发作。症状和采取的措施与患者通常在注意到症状恶化时采取的措施相似。

相似文献

1
Characterizing fibromyalgia flares: a prospective observational study.
Reumatologia. 2022;60(4):242-246. doi: 10.5114/reum.2022.118677. Epub 2022 Sep 7.
2
Fibromyalgia Flares: A Qualitative Analysis.
Pain Med. 2016 Mar;17(3):463-468. doi: 10.1111/pme.12676. Epub 2016 Mar 1.
3
Flares in rheumatoid arthritis: frequency and management. A report from the BRASS registry.
J Rheumatol. 2014 Feb;41(2):227-34. doi: 10.3899/jrheum.121521. Epub 2013 Dec 15.
6
The Lived Experience of Lupus Flares: Features, Triggers, and Management in an Australian Female Cohort.
Int J Chronic Dis. 2014;2014:816729. doi: 10.1155/2014/816729. Epub 2014 Nov 20.

引用本文的文献

1
C-reactive protein is associated with pain-type somatic symptoms independent of mental health symptoms in adolescents: Evidence from the ALSPAC study.
Brain Behav Immun Health. 2025 Aug 5;48:101082. doi: 10.1016/j.bbih.2025.101082. eCollection 2025 Oct.
2
Altered response to Toll-like receptor 4 activation in fibromyalgia: A low-dose, human experimental endotoxemia pilot study.
Brain Behav Immun Health. 2023 Nov 17;34:100707. doi: 10.1016/j.bbih.2023.100707. eCollection 2023 Dec.

本文引用的文献

1
Weather sensitivity associated with quality of life in patients with fibromyalgia.
BMC Rheumatol. 2021 May 10;5(1):14. doi: 10.1186/s41927-021-00185-4.
2
Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update.
Int J Mol Sci. 2021 Apr 9;22(8):3891. doi: 10.3390/ijms22083891.
3
Blame it on the weather? The association between pain in fibromyalgia, relative humidity, temperature and barometric pressure.
PLoS One. 2019 May 10;14(5):e0216902. doi: 10.1371/journal.pone.0216902. eCollection 2019.
4
Daily Fluctuations of Progesterone and Testosterone Are Associated With Fibromyalgia Pain Severity.
J Pain. 2018 Apr;19(4):410-417. doi: 10.1016/j.jpain.2017.11.013. Epub 2017 Dec 14.
5
Do Fibromyalgia Flares Have a Neurobiological Substrate?
Pain Med. 2016 Mar;17(3):469-475. doi: 10.1093/pm/pnw008. Epub 2016 Feb 25.
6
Fibromyalgia Flares: A Qualitative Analysis.
Pain Med. 2016 Mar;17(3):463-468. doi: 10.1111/pme.12676. Epub 2016 Mar 1.
7
'A giant mess'--making sense of complexity in the accounts of people with fibromyalgia.
Br J Health Psychol. 2013 Nov;18(4):763-81. doi: 10.1111/bjhp.12020. Epub 2013 Jan 24.
8
Dietary aspects in fibromyalgia patients: results of a survey on food awareness, allergies, and nutritional supplementation.
Rheumatol Int. 2012 Sep;32(9):2615-21. doi: 10.1007/s00296-011-2010-z. Epub 2011 Jul 22.
9
The longitudinal outcome of fibromyalgia: a study of 1555 patients.
J Rheumatol. 2011 Oct;38(10):2238-46. doi: 10.3899/jrheum.110026. Epub 2011 Jul 15.
10
Strategies used for managing symptoms by women with fibromyalgia.
J Clin Nurs. 2012 Mar;21(5-6):626-35. doi: 10.1111/j.1365-2702.2010.03501.x. Epub 2011 Feb 15.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验