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新发浸润性肺结核合并频繁呼吸道病毒感染患者的免疫状态

[Immunity in patients with new onset infiltrative pulmonary tuberculosis who suffer from frequent respiratory viral infection].

作者信息

Sukhoveĭ Iu G, Petrov S A, Popov A V, Unger I G, Argunova G A

出版信息

Probl Tuberk Bolezn Legk. 2004(5):28-31.

Abstract

The rate of respiratory viral infection in the history affects the pattern of manifestations of pulmonary tuberculosis. With the manifestation of tuberculous infection, there is a reduction in the level of mature T lymphocytes and an increase in the values of monocytic oxygen-dependent metabolism (spontaneous and stimulated HCT test). Reductions in the level of activated proliferative cell markers of the lymphocytic link (CD38+ cells, expression of receptors for IL-2, Class II HLA antigens, and receptors for transferrin), in the absolute count of B lymphocytes, in the level of EA-POM and EA-phagocytosis of monocytes and an increase in the concentration of IgM occur more than 3 times a year in patients with respiratory viral infections.

摘要

既往呼吸道病毒感染率影响肺结核的表现形式。随着结核感染的出现,成熟T淋巴细胞水平降低,单核细胞氧依赖性代谢值升高(自发和刺激的HCT试验)。呼吸道病毒感染患者每年超过3次出现淋巴细胞系活化增殖细胞标志物水平降低(CD38 +细胞、IL - 2受体、II类HLA抗原和转铁蛋白受体的表达)、B淋巴细胞绝对计数降低、单核细胞EA - POM和EA吞噬水平降低以及IgM浓度升高。

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