Eggli K, Giudici M, Ramer J, Easterbrook J, Madewell J
Department of Radiology, Pennsylvania State University, Milton S. Hershey Medical Center, Hershey.
Pediatr Radiol. 1992;22(4):257-61. doi: 10.1007/BF02019852.
Melnick-Needles syndrome is a rare connective tissue disorder producing somatic abnormalities with characteristic radiographic features. There are less than 35 documented cases reported to date. We present four new cases of Melnick-Needles Syndrome, one of which is the first reported Asian-ancestry patient. Two girls are daughters of one of Needle's original patients from family #2. Two others, from unrelated non-affected families, probably represent new mutations. All have characteristic radiographic features of the disorder.
