Baker Shannon J, Johnson Philip J, David Andrew, Cook Cristi Reeves
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA.
J Am Vet Med Assoc. 2004 Jun 15;224(12):1967-70, 1931. doi: 10.2460/javma.2004.224.1967.
Chronic gastroesophageal reflux disease was diagnosed in a 22-year-old female Tennessee Walking Horse that had signs of bruxism and ptyalism. Esophageal ulceration was detected via endoscopy. Compared with the damage to the proximal portions of the esophagus, the severity of the ulceration increased toward the gastroesophageal junction. Esophageal ulceration attributable to chronic gastric acid reflux is usually secondary to pyloric outflow obstruction in horses. In the horse of this report, there was no evidence of either a chronic pyloric or duodenal obstruction that could have resulted in esophageal ulceration. Esophageal ulceration in this horse was attributed to gastroesophageal reflux disease, a common condition in humans in which the underlying abnormality is functional incompetence of the gastroesophageal junction. Treatment is directed at decreasing gastric acidity and protecting the ulcerated mucosa. In the horse of this report, treatment was unsuccessful and the horse was euthanatized; a physical cause of gastroesophageal reflux disease was not identified during an extensive postmortem examination.
一匹22岁的雌性田纳西走马被诊断患有慢性胃食管反流病，出现了磨牙症和流涎症状。通过内窥镜检查发现了食管溃疡。与食管近端的损伤相比，溃疡的严重程度朝着胃食管交界处增加。马因慢性胃酸反流导致的食管溃疡通常继发于幽门流出道梗阻。在本报告的这匹马中，没有证据表明存在可能导致食管溃疡的慢性幽门或十二指肠梗阻。这匹马的食管溃疡归因于胃食管反流病，这是人类的一种常见病症，其潜在异常是胃食管交界处功能不全。治疗旨在降低胃酸度并保护溃疡黏膜。在本报告的这匹马中，治疗未成功，马被实施安乐死；在广泛的尸检过程中未发现胃食管反流病的确切病因。
