Kovarcík K, Valentová V
Veterinary Research Institute, Hudcova 70, Brno 621 32, Czech Republic.
Acta Virol. 2004;48(1):57-62.
In this study we showed a high degree of genetic homogeneity among recently (2002-2003) circulating Bovine respiratory syncytial virus (BRSV) strains in cattle population in the Czech Republic. These strains are in a phylogenetic tree more closely related to the Danish strains from 1995 than to the Czech strain VS97 from 1997 that shares the highest similarity with the French strain F1 and the Belgian strain P10. From the sequence analysis we deduce that the revealed high diversity between BRSV strains from 2002-2003 and those from 1997, at both nucleotide (0-11.4%) and amino acid (0-21%) level, is more likely due to distinct sources of the virus strains than to the sequence evolution.
在本研究中，我们发现捷克共和国牛群中近期（2002 - 2003年）流行的牛呼吸道合胞病毒（BRSV）毒株具有高度的遗传同质性。在系统发育树中，这些毒株与1995年的丹麦毒株的亲缘关系比与1997年的捷克毒株VS97更近，后者与法国毒株F1和比利时毒株P10具有最高的相似性。通过序列分析我们推断，2002 - 2003年的BRSV毒株与1997年的毒株在核苷酸（0 - 11.4%）和氨基酸（0 - 21%）水平上呈现出的高度差异，更可能是由于病毒毒株来源不同，而非序列进化所致。
