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六个欧洲国家乳腺癌相关的发病和死亡负担:欧洲残疾权重项目

The breast cancer related burden of morbidity and mortality in six European countries: the European Disability Weights project.

作者信息

Kruijshaar Michelle E, Barendregt Jan J

机构信息

Department of Public Health, Erasmus University Rotterdam, Rotterdam, The Netherlands.

出版信息

Eur J Public Health. 2004 Jun;14(2):141-6. doi: 10.1093/eurpub/14.2.141.

Abstract

BACKGROUND

The burden of breast cancer expressed in Disability Adjusted Life Years (DALYs) was compared for six European countries and its sensitivity to different sources of variation examined.

METHODS

DALYs were calculated using country-specific epidemiological data and European Disability Weights. Epidemiological data for 1996 were obtained for Denmark, England and Wales, France, The Netherlands, Spain and Sweden. Disability weights were empirically derived.

RESULTS

Denmark and The Netherlands lost the largest number of DALYs (approximately 1100 DALYs per 100,000 women). They were followed by England (87% of the Danish burden), France (72%), Sweden (68%) and Spain (67%). 70 to 80% of the burden was caused by mortality. Cross-national variation in disease epidemiology was the largest source of variation in the burden of breast cancer. Variation in disability weights and uncertainty in epidemiological data had smaller effects.

CONCLUSION

To compare the burden of breast cancer and most other types of cancer mortality rates provide sufficient information.

摘要

背景

比较了六个欧洲国家以伤残调整生命年(DALYs)表示的乳腺癌负担,并研究了其对不同变异来源的敏感性。

方法

使用各国特定的流行病学数据和欧洲伤残权重计算DALYs。获取了丹麦、英格兰和威尔士、法国、荷兰、西班牙和瑞典1996年的流行病学数据。伤残权重是通过实证得出的。

结果

丹麦和荷兰损失的DALYs数量最多(每10万名女性约1100个DALYs)。其次是英格兰(丹麦负担的87%)、法国(72%)、瑞典(68%)和西班牙(67%)。70%至80%的负担是由死亡率造成的。疾病流行病学的跨国差异是乳腺癌负担差异的最大来源。伤残权重的差异和流行病学数据的不确定性影响较小。

结论

为比较乳腺癌负担,对于大多数其他类型的癌症,死亡率提供了足够的信息。

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