Wieliczko A, Mazurkiewicz M, Piasecki T, Kuszczyński T
Department of Epizootiology and Veterinary Administration with Clinic, Division of Poultry Disease, Faculty of Veterinary Medicine, Agricultural University of Wrocław, Pl. Grunwaldzki 45, 50-366 Wrocław, Poland.
Pol J Vet Sci. 2004;7(2):143-7.
The ILT case was observed in laying hen farm where birds of different age (from 40 to 107 weeks) were kept in 10 flocks. A rapid spread of the disease, the decrease in egg production (in flock No. 1 it reached 58%) and higher mortality (the highest in 76 and 77 week-old birds, accounting for 0.11% and 0.36%, respectively ) was recorded during first 2 weeks of disease. Antibodies against ILT virus were detected in serum of the examined birds during the whole observation period (50 weeks after the disease outbreak). The laying hens were vaccinated at 8 weeks of age and boosted after 5 weeks. The vaccine was applied in drinking water, in a dose twice as high as usually recommended per one bird. Immunopropylaxis efficiency was estimated on the basis of immunological response in birds (serum samples, ILT ELISA kit, Guildhay Ltd.) and general health status of hens in flocks. Postvaccinal immunity, the presence of specific antibodies against ILT, was observed in all birds during the observation period (51 weeks). During that time GMT value ranged from 8261,3 (week 10) to 5196 (week 51) after the second vaccination, and CV amounted in this period to 41.1% and 51%, respectively. Subsequently, clinical symptoms of the disease disappeared and the egg production, as well as mortality, returned to the level of technological norms for laying hens.
在一个蛋鸡养殖场观察到传染性喉气管炎（ILT）病例，该养殖场饲养了10群不同年龄（40至107周）的鸡。在疾病的前两周，记录到疾病迅速传播、产蛋量下降（第1群下降至58%）以及死亡率升高（76周龄和77周龄的鸡死亡率最高，分别为0.11%和0.36%）。在整个观察期（疾病爆发后50周）内，在被检测鸡的血清中均检测到抗ILT病毒抗体。蛋鸡在8周龄时接种疫苗，5周后进行加强免疫。疫苗通过饮水接种，剂量是通常每只鸡推荐剂量的两倍。根据鸡的免疫反应（血清样本，ILT ELISA试剂盒，Guildhay有限公司）和鸡群中母鸡的总体健康状况评估免疫预防效果。在观察期（51周）内，所有鸡均观察到疫苗接种后的免疫力，即存在抗ILT的特异性抗体。在此期间，第二次接种疫苗后，GMT值范围从第10周的8261.3到第51周的5196，此期间CV分别为41.1%和51%。随后，疾病的临床症状消失，产蛋量和死亡率恢复到蛋鸡的技术规范水平。
