Phillips Claire, Willis David, Cramb Jim, Chicas-Angulo Franc, Sexton Maree
Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Australas Radiol. 2004 Jun;48(2):188-94. doi: 10.1111/j.1440-1673.2004.01295.x.
Craniospinal irradiation is an important technique for the treatment of a number of paediatric malignancies. The conventional technique uses photons for all fields and does not exploit the benefits of CT and computer planning systems. The present paper describes a modification of the conventional technique in which both photons and electrons are used for the spinal field (mixed-beam technique). Computed tomography images and a planning computer are used for the selection of field junctions, electron beam energy and dosimetry. The intention of the technique is to reduce radiotherapy toxicity. A discussion of the potential benefits is presented.
全脑全脊髓照射是治疗多种儿童恶性肿瘤的一项重要技术。传统技术在所有照射野均使用光子，未利用CT和计算机计划系统的优势。本文描述了一种对传统技术的改进方法，即在脊髓照射野同时使用光子和电子（混合束技术）。利用计算机断层扫描图像和计划计算机来选择照射野衔接、电子束能量及剂量测定。该技术旨在降低放射治疗的毒性。文中对潜在益处进行了讨论。
