Cermelj M, Negro F, Schijman E, Ferro A M, Acerenza M, Pollola J
Instituto Henry Moore-PROSAM, Aguer 1248, Buenos Aires, 1425, Argentina
Haemophilia. 2004 Jul;10(4):405-7. doi: 10.1111/j.1365-2516.2004.00916.x.
A case of a 3-year-old boy with severe haemophilia A who had a successful neurosurgical drainage of a combined spontaneous left temporal subdural and intra-parenchimal haematoma is reported. Surgical intervention was required because of clinical worsening during conservative treatment with dexamethasone and factor VIII (FVIII) replacement therapy. Continuous FVIII infusion was given before, during and after the procedure. There were no surgical complications and neurological examination remains intact. Neurosurgical interventions may be reserved for special, high-risk cases, as the one presented.
报告了一例3岁重度甲型血友病男孩,成功进行了神经外科手术引流自发性左颞部硬膜下和脑实质内混合血肿。由于在使用地塞米松和因子VIII(FVIII)替代疗法进行保守治疗期间临床症状恶化,因此需要进行手术干预。在手术前、手术期间和手术后均持续输注FVIII。未出现手术并发症,神经检查结果保持完好。神经外科干预可能适用于像本文所呈现的此类特殊的高危病例。