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腹腔镜下贲门失弛缓症Heller肌切开术的功能结果:与开放手术的对比研究。

Functional results after laparoscopic Heller myotomy for achalasia: A comparative study to open surgery.

作者信息

Douard Richard, Gaudric Marianne, Chaussade Stanislas, Couturier Daniel, Houssin Didier, Dousset Bertrand

机构信息

Department of Surgery, Cochin University Hospital, Paris, France.

出版信息

Surgery. 2004 Jul;136(1):16-24. doi: 10.1016/j.surg.2004.01.011.

Abstract

BACKGROUND

Prospective studies comparing laparoscopic to open Heller myotomy for esophageal achalasia are lacking. The aim of this study was to compare functional outcome after laparoscopic and open Heller myotomy for esophageal achalasia.

METHODS

Eighty-two patients who underwent Heller-Dor myotomy for achalasia, via laparoscopy (n=52) or open surgery (n=30) were recorded prospectively (1993-2002). Median follow-up was 51 (12-111) months. Perioperative functional data were assessed via dysphagia and overall clinical (dysphagia, chest pain, regurgitation, gastroesophageal reflux) scores.

RESULTS

In laparoscopy patients, the operative time was longer (145 [95-290] vs 120 [70-230] minutes, P <.0001); the postoperative hospital stay and feeding resumption time was shorter (4 [2-25] vs 7.5 [5-18] days, P <.0001 and 2 [1-15] vs 4 [1-14] days, P <.0001). Three mucosal tears necessitated conversion to open surgery (6%). The rates of " excellent" or " satisfactory" results after laparoscopic and open surgery were 92% (n=48/52) versus 93% (n=28/30), and 83% (n=43/52) versus 83% (n=25/30) on overall clinical score. In both groups, the overall clinical score indicated significant improvement during 12-month follow-up. The laparoscopy and open surgery symptomatic gastroesophageal reflux rates were 10% and 7%, respectively.

CONCLUSIONS

Laparoscopic Heller myotomy favorably compares with open surgery regarding dysphagia relief and gastroesophageal reflux rate. Overall clinical score indicates gradual improvement in patient functional status during 12-month follow-up.

摘要

背景

目前缺乏比较腹腔镜下与开放性贲门失弛缓症Heller肌切开术的前瞻性研究。本研究的目的是比较腹腔镜与开放性贲门失弛缓症Heller肌切开术后的功能结局。

方法

前瞻性记录了82例行Heller-Dor肌切开术治疗贲门失弛缓症的患者,其中52例行腹腔镜手术,30例行开放手术(1993 - 2002年)。中位随访时间为51(12 - 111)个月。通过吞咽困难和总体临床(吞咽困难、胸痛、反流、胃食管反流)评分评估围手术期功能数据。

结果

腹腔镜手术患者的手术时间较长(145[95 - 290]分钟对120[70 - 230]分钟,P <.0001);术后住院时间和恢复进食时间较短(4[2 - 25]天对7.5[5 - 18]天,P <.0001和2[1 - 15]天对4[1 - 14]天,P <.0001)。3例黏膜撕裂需要转为开放手术(6%)。腹腔镜手术和开放手术后“优秀”或“满意”结果的比例在总体临床评分方面分别为92%(n = 48/52)对93%(n = 28/30),以及83%(n = 43/52)对83%(n = 25/30)。在两组中,总体临床评分在12个月随访期间均显示出显著改善。腹腔镜手术和开放手术的症状性胃食管反流率分别为10%和7%。

结论

在缓解吞咽困难和胃食管反流率方面,腹腔镜Heller肌切开术与开放手术相比具有优势。总体临床评分表明患者功能状态在12个月随访期间逐渐改善。

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