Weksler N, Ovadia L
Department of Anesthesiology, Hillel Yaffe Memorial Hospital, Hadera, Israel.
J Anesth. 1989 Mar 1;3(1):40-2. doi: 10.1007/s0054090030040.
Non cardiogenic pulmonary edema is a rare complication of upper airway obstruction. Its etiology is controversial, but probably can be explained by the Starling's law, when the large negative intrathoracic pressure generated exceeds the intravascular and interstitial pressures, shifting fluids from capillaries to interstitium and alveoli. In addition, alteration of capillary permeability potentiates fluid migration. We present herein, a case of non cardiogenic pulmonary edema following relief of upper airway obstruction in a 14 years old girl underwent surgical repair of cleft palate. Cardiogenic pulmonary edema could be excluded by a normal CVP, wedge pressure and four chamber echocardiography. The edema fluid: plasma protein ratio greater than 0.7 can indicate an increased capillary permeability. Mendelson's syndrome could be ruled out by the rapid improvement seen and the soft clinical course.
非心源性肺水肿是上呼吸道梗阻的一种罕见并发症。其病因存在争议,但可能可用斯塔林定律来解释,即当产生的巨大胸内负压超过血管内压和间质压时,液体就会从毛细血管转移至间质和肺泡。此外,毛细血管通透性的改变会增强液体迁移。在此,我们报告一例14岁行腭裂手术修复的女孩,在上呼吸道梗阻解除后发生非心源性肺水肿的病例。中心静脉压、楔压及四腔心超声心动图均正常可排除心源性肺水肿。水肿液与血浆蛋白比值大于0.7可提示毛细血管通透性增加。所见的迅速好转及病情的平稳过程可排除门德尔松综合征。