Ito Yasuhiko, Nishiyama Hiroyuki, Higashi Shin, Kinoshita Hidefumi, Ito Noriyuki, Yamamoto Shingo, Kamoto Toshiyuki, Ogawa Osamu
Department of Urology, Kyoto University Graduate School of Medicine.
Hinyokika Kiyo. 2004 May;50(5):335-8.
We report 3 cases of prostatic involvement of transitional cell carcinomas (TCCs). All cases presented positive urinary cytology after intravesical instillation of Bacillus Calmette-Guerin (BCG) and then random biopsy of bladder and transurethral resection (TUR)-biopsy of prostatic urethra were performed. TUR-biopsy demonstrated TCC in the prostate, although random biopsy failed to detect tumors in the bladder in all cases. Case 1 was treated with cystourethrectomy with ileal conduit, case 2 was treated with cystourethrectomy with bilateral ureterocutaneostomy and case 3 was treated with cystectomy with orthotopic ileal neobladder reconstruction. All cases are alive with no evidence of disease. TUR-biopsy of prostatic urethra should be perfomed when patients present positive urinary cytology after BCG instillation therapy, because prostatic involvement of TCC associated with bladder carcinoma in situ is not rare.
我们报告3例移行细胞癌（TCC）累及前列腺的病例。所有病例在膀胱内灌注卡介苗（BCG）后尿细胞学检查均呈阳性，随后进行了膀胱随机活检及前列腺尿道经尿道切除术（TUR）活检。尽管所有病例的随机活检均未能在膀胱中检测到肿瘤，但TUR活检显示前列腺存在TCC。病例1接受了回肠代膀胱术的膀胱尿道切除术，病例2接受了双侧输尿管皮肤造口术的膀胱尿道切除术，病例3接受了原位回肠新膀胱重建术的膀胱切除术。所有病例均存活，无疾病证据。当患者在BCG灌注治疗后尿细胞学检查呈阳性时，应进行前列腺尿道TUR活检，因为与原位膀胱癌相关的TCC累及前列腺并不罕见。
