Nakeeb A, Lillemoe K D, Grosfeld J L
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Minerva Chir. 2004 Apr;59(2):151-63.
Surgical resection of pancreatic adenocarcinoma offers the only chance for long-term cure. Over the past 2 decades significant advances have been made in both the surgical techniques and the perioperative care of patients with pancreatic cancer. The operative management of pancreatic cancer involving the head, neck, and uncinate process consists of 2 phases: first, assessing tumor resectability and then, if the tumor is resectable, completing a pancreaticoduodenectomy and restoring gastrointestinal continuity. In this article, we describe our current techniques for resection of pancreatic cancer, review operative palliation for unresectable cancer, and discuss several controversies in the operative management of pancreatic cancer including: 1) the role of extended lymphadenectomy, 2) pylorus preservation and 3) pancreaticojejunostomy versus pancreaticogastrostomy for pancreatic duct reconstruction.
手术切除胰腺腺癌是实现长期治愈的唯一机会。在过去20年里,胰腺癌患者的手术技术和围手术期护理都取得了重大进展。涉及胰头、颈部和钩突的胰腺癌手术管理包括两个阶段:首先,评估肿瘤的可切除性;然后,如果肿瘤可切除,则完成胰十二指肠切除术并恢复胃肠道连续性。在本文中,我们描述了目前胰腺癌切除的技术,回顾了不可切除癌症的手术姑息治疗,并讨论了胰腺癌手术管理中的几个争议问题,包括:1)扩大淋巴结清扫的作用,2)保留幽门,以及3)胰管重建时胰空肠吻合术与胰胃吻合术的比较。