UCSF Helen Diller Family Comprehensive Cancer Center.
J Natl Compr Canc Netw. 2012 Jun 1;10(6):703-13. doi: 10.6004/jnccn.2012.0073.
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pancreatic Adenocarcinoma discuss the workup and management of tumors of the exocrine pancreas. These NCCN Guidelines Insights provide a summary and explanation of major changes to the 2012 NCCN Guidelines for Pancreatic Adenocarcinoma. The panel made 3 significant updates to the guidelines: 1) more detail was added regarding multiphase CT techniques for diagnosis and staging of pancreatic cancer, and pancreas protocol MRI was added as an emerging alternative to CT; 2) the use of a fluoropyrimidine plus oxaliplatin (e.g., 5-FU/leucovorin/oxaliplatin or capecitabine/oxaliplatin) was added as an acceptable chemotherapy combination for patients with advanced or metastatic disease and good performance status as a category 2B recommendation; and 3) the panel developed new recommendations concerning surgical technique and pathologic analysis and reporting.
美国国家综合癌症网络（NCCN）临床实践指南（NCCN 指南）讨论了外分泌胰腺肿瘤的检查和治疗。本 NCCN 指南解读概要介绍了 2012 年版 NCCN 胰腺腺癌指南的重大更新。专家组对指南进行了 3 项重大更新：1） 更详细地介绍了多期 CT 技术在胰腺癌诊断和分期中的应用，并将胰腺方案 MRI 作为 CT 的新兴替代方法；2） 氟嘧啶加奥沙利铂（例如，5-FU/亚叶酸钙/奥沙利铂或卡培他滨/奥沙利铂）的使用被添加为一种可接受的化疗联合方案，用于晚期或转移性疾病且体能状态良好的患者，作为 2B 类推荐；3） 专家组制定了关于手术技术和病理分析及报告的新建议。
