Nakajima M, Manabe T, Yagi S
Department of Human Pathology, Kawasaki Medical School, Kurashiki, Japan.
Acta Cytol. 1992 Sep-Oct;36(5):731-6.
A case in which mesothelioma cells appeared in sputum is reported. There has been only one earlier reported case of the exfoliation of mesothelioma cells into sputum. A postmortem examination in our case disclosed a lepidic growth of mesothelioma cells along the alveolar wall of the lung, suggesting that this mode of spread in the lung was probably responsible for the shedding of tumor cells in sputum. Cytopathologists should be aware of this possibility in differentiating this entity from adenocarcinoma involving the pleura.
本文报告了一例痰液中出现间皮瘤细胞的病例。此前仅有一例间皮瘤细胞脱落至痰液中的病例报告。我们这例病例的尸检显示，间皮瘤细胞沿肺泡壁呈鳞屑样生长，提示肺部的这种扩散方式可能是肿瘤细胞脱落至痰液中的原因。细胞病理学家在将该实体与累及胸膜的腺癌进行鉴别时应意识到这种可能性。
