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含氟口香糖对儿童唾液氟浓度和菌斑pH值的功效。

The efficacy of a fluoride chewing gum on salivary fluoride concentration and plaque pH in children.

作者信息

Oztaş Nurhan, Bodur Haluk, Olmez Ayşegül, Berkkan Aysel, Cula Serpil

机构信息

Department of Pediatric Dentistry, Gazi University, Biskek cad 82, Ankara 06510, Turkey.

出版信息

J Dent. 2004 Aug;32(6):471-7. doi: 10.1016/j.jdent.2004.03.002.

Abstract

OBJECTIVES

The purpose of this study was therefore to study the influence of different chewing times on the salivary F concentration and on the recovery of plaque pH directly after a sucrose rinse on both the chewing and the non-chewing side.

METHODS

For this purpose, one piece of sugar free chewing gum was chewed to 10 healthy subjects (aged 8-10 years, 5 male and 5 female children). Subjects refrained from toothbrushing for 3 days. On the fourth day, they rinsed for 1 min with 10 microl of a 10% sucrose solutions. After 8 min, chewing gum was given and started to chew for either 5, 10, 20, 30, 45 min or control (sucrose rinse). Thus, altogether six test sessions were repeated at one week intervals. Measurements of F concentration in saliva and pH of approximal plaque were carried out at two contralateral sites for up to 60 min.

RESULTS

Higher salivary F concentrations were found on the chewing side than on the non-chewing side (expressed as) (p<0.05). But, the difference between the chewing and the non-chewing side was not obvious for the plaque pH (expressed as AUC) (p>0.05). Therefore, this study showed that: (1) the F concentrations in saliva after chewing a F containing chewing gum had only small numerical differences among the various chewing times, with the exception for 5 min. All chewing time periods showed statistically significant differences between chewing and non-chewing side. (2) The prolonged chewing time increased the plaque pH recovery after a sucrose rinse (p<0.05) but there was no statistically significant difference on both of the chewing and non-chewing side (p>0.05).

CONCLUSION

The results of this study indicated that a prolonged chewing time was favorable to the plaque pH recovery after a sucrose rinse and, to a certain extent, to the salivary fluoride concentration. Also it was shown that the F concentration in saliva was strongly dependent on which side the subject chewed on.

摘要

目的

因此,本研究的目的是探讨不同咀嚼时间对唾液氟浓度以及在蔗糖漱口后即刻咀嚼侧和非咀嚼侧菌斑pH值恢复的影响。

方法

为此,让10名健康受试者(8 - 10岁,5名男性和5名女性儿童)咀嚼一片无糖口香糖。受试者3天不刷牙。在第四天,他们用10微升10%的蔗糖溶液漱口1分钟。8分钟后,给受试者口香糖并开始咀嚼5、10、20、30、45分钟或进行对照(蔗糖漱口)。因此,总共六个测试阶段以一周的间隔重复进行。在两个对侧部位测量唾液中的氟浓度和邻面菌斑的pH值,持续60分钟。

结果

咀嚼侧的唾液氟浓度高于非咀嚼侧(表示为)(p<0.05)。但是,咀嚼侧和非咀嚼侧之间的菌斑pH值差异不明显(表示为AUC)(p>0.05)。因此,本研究表明:(1)咀嚼含氟口香糖后,唾液中的氟浓度在不同咀嚼时间之间只有很小的数值差异,但5分钟除外。所有咀嚼时间段在咀嚼侧和非咀嚼侧之间均显示出统计学上的显著差异。(2)延长咀嚼时间可提高蔗糖漱口后菌斑pH值的恢复(p<0.05),但在咀嚼侧和非咀嚼侧均无统计学上的显著差异(p>0.05)。

结论

本研究结果表明,延长咀嚼时间有利于蔗糖漱口后菌斑pH值的恢复,并在一定程度上有利于唾液氟浓度的提高。此外,还表明唾液中的氟浓度强烈依赖于受试者咀嚼的是哪一侧。

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