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饮食组合对小儿液体镇痛药摄入后牙菌斑pH值恢复的影响。

Effect of dietary combinations on plaque pH recovery after the intake of pediatric liquid analgesics.

作者信息

Saeed Shaam, Bshara Nada, Trak Juliana, Mahmoud Ghiath

机构信息

Department of Pediatric Dentistry, School of Dentistry, Damascus University, Damascus, Syrian Arab Republic.

Department of Analytical and Food Chemistry, School of Pharmacy, Damascus University, Damascus, Syrian Arab Republic.

出版信息

Eur J Dent. 2015 Jul-Sep;9(3):340-345. doi: 10.4103/1305-7456.163220.

Abstract

OBJECTIVES

To study the effect of water, halloumi cheese and sugar-free (SF) chewing gum on plaque pH recovery after the intake of sweetened PLAs.

SETTINGS AND DESIGN

A randomized clinical trial was conducted on 17 children (10 females, 7 males) aged 11-12 years with DFT/dft of more than 3.

MATERIALS AND METHODS

Each volunteer tested paracetamol and ibuprofen suspension alone or followed with water, halloumi cheese or SF gum, as well as 10% sucrose and 10% sorbitol as controls. Plaque pH was measured using the sampling method before and after 5, 10, 15, 20, 30 min of ingestion.

STATISTICAL ANALYSIS

Statistical analysis was performed using analysis of variance followed by least significant difference test to assess minimum pH (min pH), maximum pH drop (ΔpH), and the area under baseline pH, and P value was set as 0.05.

RESULTS

Both ibuprofen and paracetamol were not significantly different from 10% sucrose in terms of min pH, ΔpH, and area under baseline pH except for min pH of ibuprofen (P = 0.034). Water and halloumi cheese did not have a significant effect on plaque pH recovery after the intake of both analgesics as min pH, ΔpH, and area under baseline pH were similar to 10% sucrose except for min pH of ibuprofen + water (P = 0.048). However, plaque pH variables after chewing SF gum for 20 min were similar to 10% sorbitol.

CONCLUSION

Chewing SF gum immediately after the intake of sweetened PLAs for 20 min restores plaque pH and could be recommended as a complementary aid in caries prevention.

摘要

目的

研究水、哈洛米奶酪和无糖口香糖对摄入含糖口含片后菌斑pH值恢复的影响。

设置与设计

对17名年龄在11 - 12岁、龋失补牙面数(DFT/dft)超过3的儿童(10名女性,7名男性)进行了一项随机临床试验。

材料与方法

每位志愿者单独测试对乙酰氨基酚和布洛芬混悬液,随后分别用水、哈洛米奶酪或无糖口香糖,以及10%蔗糖和10%山梨醇作为对照。在摄入后5、10、15、20、30分钟,采用取样法测量菌斑pH值。

统计分析

采用方差分析,随后进行最小显著差检验,以评估最低pH值(min pH)、最大pH值下降(ΔpH)和基线pH值下的面积,P值设定为0.05。

结果

就最低pH值、ΔpH和基线pH值下的面积而言,布洛芬和对乙酰氨基酚与10%蔗糖均无显著差异,但布洛芬的最低pH值除外(P = 0.034)。水和哈洛米奶酪对摄入两种镇痛药后的菌斑pH值恢复没有显著影响,因为最低pH值、ΔpH和基线pH值下的面积与10%蔗糖相似,但布洛芬+水的最低pH值除外(P = 0.048)。然而,咀嚼20分钟无糖口香糖后的菌斑pH值变量与10%山梨醇相似。

结论

在摄入含糖口含片后立即咀嚼20分钟无糖口香糖可恢复菌斑pH值,可作为预防龋齿的辅助方法推荐。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba54/4569983/f53a5e0c8437/EJD-9-340-g002.jpg

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