McKendry Moira, McGloin Helen, Saberi Debbie, Caudwell Libby, Brady Anthony R, Singer Mervyn
Bloomsbury Institute of Intensive Care Medicine, Department of Medicine and Wolfson Institute of Biomedical Research, University College London, Middlesex Hospital, London W1T 3AA.
BMJ. 2004 Jul 31;329(7460):258. doi: 10.1136/bmj.38156.767118.7C. Epub 2004 Jul 8.
To assess whether a nurse led, flow monitored protocol for optimising circulatory status in patients after cardiac surgery reduces complications and shortens stay in intensive care and hospital.
Randomised controlled trial.
Intensive care unit and cardiothoracic unit of a university teaching hospital.
174 patients who underwent cardiac surgery between April 2000 and January 2003.
Patients were allocated to conventional haemodynamic management or to an algorithm guided by oesophageal Doppler flowmetry to maintain a stroke index above 35 ml/m2.
26 control patients had postoperative complications (two deaths) compared with 17 (four deaths) protocol patients (P = 0.08). Duration of hospital stay in the protocol group was significantly reduced from a median of nine (interquartile range 7-12) days to seven (7-10) days (P = 0.02). The mean duration of hospital stay was reduced from 13.9 to 11.4 days, a saving in hospital bed days of 18% (95% confidence interval -12% to 47%). Usage of intensive care beds was reduced by 23% (-8% to 59%).
A nurse delivered protocol for optimising circulatory status in the early postoperative period after cardiac surgery may significantly shorten hospital stay.
评估由护士主导、进行血流监测的方案,能否优化心脏手术后患者的循环状态,减少并发症并缩短重症监护及住院时间。
随机对照试验。
一所大学教学医院的重症监护病房和心胸外科病房。
2000年4月至2003年1月期间接受心脏手术的174例患者。
将患者分配至接受传统血流动力学管理或由食管多普勒血流测定法指导的算法组,以维持每搏输出量指数高于35ml/m²。
26例对照组患者出现术后并发症(2例死亡),而方案组为17例(4例死亡)(P = 0.08)。方案组的住院时间显著缩短,从中位数9天(四分位间距7 - 12天)降至7天(7 - 10天)(P = 0.02)。平均住院时间从13.9天降至11.4天,节省了18%的住院床位日(95%置信区间 -12%至47%)。重症监护床位的使用减少了23%(-8%至59%)。
一项由护士实施的用于优化心脏手术后早期循环状态的方案,可能会显著缩短住院时间。