Nishizawa Koji, Kobayashi Takashi, Mitsumori Kenji, Watanabe Jun, Ogura Keiji
Department of Urology, Hamamatsu Rosai Hospital, Shizuoka, Japan.
Urology. 2004 Jul;64(1):79-83. doi: 10.1016/j.urology.2004.03.009.
To evaluate and minimize the duration of clean intermittent catheterization (CIC) required after interstitial laser coagulation of the prostate in patients with benign prostatic hyperplasia.
Patients who did not show sufficient improvement in lower urinary tract symptoms or voiding dysfunctions with alpha-1 adrenergic blockers, and who agreed to undergo interstitial laser coagulation of the prostate, were enrolled in this study. Postoperatively, the indwelling Foley catheters were removed by the next morning. Patients were then required to undertake CIC with alpha-1 adrenergic blockade therapy until the postvoid residual urine volume decreased to less than 100 mL.
Seventy-nine patients underwent interstitial laser coagulation of the prostate, and 70 underwent catheter-free trials by postoperative day 1. The mean age and preoperative prostate volume of these 70 patients was 70.3 years (SD 8.7) and 49.6 cm3 (SD 34.8), respectively. Forty-three patients experienced postoperative urinary retention, and 37 of these underwent CIC. The median postoperative catheterization time was 3 days (range 0 to 31), and all patients eventually became catheter free. Univariate analysis showed that postoperative urinary retention was associated with a preoperative prostate volume of 30 cm3 or larger, a maximal flow rate of less than 6 mL/s, and a postvoid residual urine volume of 100 mL or greater. Multivariate analysis showed that a preoperative prostate volume of 30 cm3 or larger was the most significant predictor of postoperative urinary retention.
More than 60% of the patients experienced urinary retention after interstitial laser coagulation of the prostate. However, the results of the present study suggested that CIC and alpha-1 adrenergic blockade therapy could manage post-treatment urinary retention with a relatively short catheterization time.
评估并尽量缩短良性前列腺增生患者前列腺间质激光凝固术后所需的清洁间歇性导尿(CIC)时间。
对使用α-1肾上腺素能阻滞剂后下尿路症状或排尿功能改善不充分且同意接受前列腺间质激光凝固术的患者进行研究。术后,次日清晨拔除留置的 Foley 导尿管。然后要求患者在接受α-1肾上腺素能阻滞剂治疗的同时进行 CIC,直至残余尿量降至100 mL以下。
79例患者接受了前列腺间质激光凝固术,70例在术后第1天进行了无导尿试验。这70例患者的平均年龄和术前前列腺体积分别为70.3岁(标准差8.7)和49.6 cm³(标准差34.8)。43例患者术后发生尿潴留,其中37例接受了CIC。术后导尿时间中位数为3天(范围0至31天),所有患者最终均不再需要导尿。单因素分析显示,术后尿潴留与术前前列腺体积30 cm³或更大、最大尿流率低于6 mL/s以及残余尿量100 mL或更多有关。多因素分析显示,术前前列腺体积30 cm³或更大是术后尿潴留最显著的预测因素。
超过60%的患者在前列腺间质激光凝固术后发生尿潴留。然而,本研究结果表明,CIC和α-1肾上腺素能阻滞剂治疗可在相对较短的导尿时间内处理治疗后尿潴留。