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钬激光剜除术治疗尿潴留患者的前列腺

Holmium laser enucleation of prostate for patients in urinary retention.

作者信息

Elzayat Ehab A, Habib Enmar I, Elhilali Mostafa M

机构信息

Division of Urology, McGill University School of Medicine, Montreal, Quebec, Canada.

出版信息

Urology. 2005 Oct;66(4):789-93. doi: 10.1016/j.urology.2005.04.049.

Abstract

OBJECTIVES

To evaluate holmium laser enucleation of the prostate in patients presenting in urinary retention secondary to benign prostatic hyperplasia.

METHODS

From May 2000 to May 2004, 169 patients, with a mean age of 74 years, who presented in urinary retention secondary to benign prostatic hyperplasia underwent holmium laser enucleation of the prostate. The mean urinary volume drained at catheterization was 670 mL (range 132 to 2000). All the patients were assessed preoperatively, 1, 3, 6, and 12 months postoperatively, and every year thereafter. All the patients were evaluated by physical examination, digital rectal examination, symptom evaluation using the International Prostate Symptom Score questionnaire, uroflowmetry (whenever possible), postvoid residual urine volume measurement, and prostate-specific antigen. The mean preoperative prostate volume estimated by transrectal ultrasonography was 101 cm3 (range 20 to 351).

RESULTS

The mean catheter time and hospital stay was 1.6 and 1.7 days, respectively. The peak urinary flow rate, postvoid residual urine volume, and International Prostate Symptom Score and quality-of-life score were significantly improved by 1 month after surgery and continued to improve during subsequent follow-up. Three patients (1.75%) were unable to void postoperatively; one required a suprapubic catheter and two used clean intermittent catheterization. Four patients (2.4%) were receiving anticoagulant therapy and required blood transfusion. Bladder neck contracture and urethral stricture developed in 1.7% and 1.2%, respectively.

CONCLUSIONS

Holmium laser enucleation of the prostate represents a safe and effective treatment for patients with benign prostatic hyperplasia presenting in urinary retention. It has low morbidity and provides immediate symptom and voiding improvement.

摘要

目的

评估钬激光前列腺剜除术治疗良性前列腺增生继发尿潴留患者的效果。

方法

2000年5月至2004年5月,169例平均年龄74岁、因良性前列腺增生继发尿潴留的患者接受了钬激光前列腺剜除术。导尿时引出的平均尿量为670毫升(范围132至2000毫升)。所有患者在术前、术后1个月、3个月、6个月和12个月以及此后每年进行评估。所有患者均通过体格检查、直肠指检、使用国际前列腺症状评分问卷进行症状评估、尿流率测定(尽可能进行)、排尿后残余尿量测量以及前列腺特异性抗原进行评估。经直肠超声估计的术前平均前列腺体积为101立方厘米(范围20至351立方厘米)。

结果

平均导尿时间和住院时间分别为1.6天和1.7天。术后1个月时,最大尿流率、排尿后残余尿量、国际前列腺症状评分和生活质量评分显著改善,并在随后的随访期间持续改善。3例患者(1.75%)术后无法排尿;1例需要耻骨上导管,2例采用清洁间歇性导尿。4例患者(2.4%)接受抗凝治疗并需要输血。膀胱颈挛缩和尿道狭窄的发生率分别为1.7%和1.2%。

结论

钬激光前列腺剜除术是治疗良性前列腺增生继发尿潴留患者安全有效的方法。其发病率低,能立即改善症状和排尿情况。

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