Desai Mahesh R, Kukreja Rajesh A, Desai Mihir M, Mhaskar Sumeet S, Wani Kishore A, Patel Snehal H, Bapat Sharad D
Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, India.
J Urol. 2004 Aug;172(2):565-7. doi: 10.1097/01.ju.0000130752.97414.c8.
We compared postoperative outcomes among tubeless, conventional large bore nephrostomy drainage and small bore nephrostomy drainage following percutaneous nephrostolithotomy (PCNL) in a prospective randomized fashion.
Between January and June 2001, 30 patients undergoing PCNL were randomized to receive conventional large bore (20Fr) nephrostomy drainage (group 1, 10 patients), small bore (9Fr) nephrostomy drainage (group 2, 10 patients) or no nephrostomy drainage (group 3, 10 patients). Inclusion criteria included a single subcostal tract, uncomplicated procedure, normal preoperative renal function and complete stone clearance. Factors compared among the 3 groups were postoperative analgesia requirement, urinary extravasation, duration of hematuria, duration of urinary leak, decrease in hematocrit and hospital stay.
The postoperative analgesic requirement was significantly higher in group 1 (217 mg) compared to groups 2 (140 mg, p <0.05) and 3 (87.5 mg, p <0.0001). Patients in group 3 had a significantly shorter duration (4.8 hours) of urinary leak through the percutaneous renal tract compared to patients in groups 1 (21.4 hours, p <0.05) and 2 (13.2 hours, p <0.05). Hospital stay was significantly shorter in group 3 (3.4 days) compared to groups 1 (4.4 days, p <0.05) and 2 (4.3 days, p <0.05). All 3 groups were similar in terms of operative time, duration of hematuria and decrease in hematocrit. Postoperative ultrasound did not reveal significant urinary extravasation in any case.
Tubeless PCNL is associated with the least postoperative pain, urinary leakage and hospital stay. Small bore nephrostomy drainage may be a reasonable option in patients in whom the incidence of stent dysuria is likely to be higher.
我们以前瞻性随机方式比较了经皮肾镜取石术(PCNL)后无管引流、传统大口径肾造瘘引流和小口径肾造瘘引流的术后结果。
2001年1月至6月期间,30例行PCNL的患者被随机分为接受传统大口径(20Fr)肾造瘘引流组(第1组,10例患者)、小口径(9Fr)肾造瘘引流组(第2组,10例患者)或无肾造瘘引流组(第3组,10例患者)。纳入标准包括单一肋下通道、手术无并发症、术前肾功能正常及结石完全清除。比较3组之间的因素有术后镇痛需求、尿液外渗、血尿持续时间、尿漏持续时间、血细胞比容下降情况及住院时间。
第1组术后镇痛需求量(217mg)显著高于第2组(140mg,p<0.05)和第3组(87.5mg,p<0.0001)。与第1组(21.4小时,p<0.05)和第2组(13.2小时,p<0.05)的患者相比,第3组患者经皮肾通道的尿漏持续时间显著更短(4.8小时)。与第1组(4.4天,p<0.05)和第2组(4.3天,p<0.05)相比,第3组的住院时间显著更短(3.4天)。所有3组在手术时间、血尿持续时间和血细胞比容下降方面相似。术后超声检查在任何情况下均未发现明显的尿液外渗。
无管PCNL术后疼痛、尿漏和住院时间最少。对于支架排尿困难发生率可能较高的患者,小口径肾造瘘引流可能是一种合理的选择。