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冠状动脉搭桥术中取桡动脉后手部功能的结果评估

Outcome assessment of hand function after radial artery harvesting for coronary artery bypass.

作者信息

Allen Robert H, Szabo Robert M, Chen James L

机构信息

Department of Orthopaedics, University of California, Davis, Sacramento, CA 95817, USA.

出版信息

J Hand Surg Am. 2004 Jul;29(4):628-37. doi: 10.1016/j.jhsa.2004.04.013.

Abstract

The radial artery has gained widespread acceptance as a conduit for coronary artery bypass. Advantages include minimal donor site discomfort, ease of handling, excellent early patency rates, and the possibility of freedom from late conduit atherosclerosis. Although most series describe minimal morbidity, a significant incidence of radial sensory neuropathy and isolated instances of hand claudication and ischemia have been reported. We performed an outcome study utilizing the Short Form-36, the Upper Limb-Disabilities of Arm, Shoulder and Hand, and a modified self-administered hand diagram to compare 288 patients undergoing coronary artery bypass utilizing the radial artery with a control group of 174 patients undergoing coronary artery bypass without the radial artery. The data were analyzed by the t test for continuous variables and the chi-square test for categorical variables, and subsequently a multivariate regression model was constructed. No patients developed hand claudication or ischemia. Although there was an incidence of radial sensory neuropathy of 9.9% associated with radial artery harvest, it was not significantly higher than the incidence in the control group (5.2%, p =.16). Intrinsic patient factors such as obesity, age, diabetes, and peripheral vascular disease were the principal determinants of overall health and quality of life issues.

摘要

桡动脉作为冠状动脉旁路移植的血管 conduit 已获得广泛认可。其优点包括供体部位不适轻微、易于操作、早期通畅率极佳,以及可能避免晚期血管 conduit 动脉粥样硬化。尽管大多数系列报道的发病率较低,但已报告有显著比例的桡神经感觉神经病以及孤立的手部间歇性跛行和缺血病例。我们进行了一项结局研究,使用简短健康调查问卷-36、上肢-臂、肩和手功能障碍量表,以及一份改良的自我填写手部示意图,以比较 288 例行冠状动脉旁路移植且使用桡动脉的患者与 174 例未使用桡动脉行冠状动脉旁路移植的对照组患者。连续变量数据采用 t 检验分析,分类变量采用卡方检验分析,随后构建多变量回归模型。无患者发生手部间歇性跛行或缺血。尽管与桡动脉获取相关的桡神经感觉神经病发病率为 9.9%,但并不显著高于对照组的发病率(5.2%,p = 0.16)。肥胖、年龄、糖尿病和外周血管疾病等患者内在因素是总体健康和生活质量问题的主要决定因素。

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