Shah Salman A, Chark Davin, Williams Judson, Hessheimer Amelia, Huh Jeannie, Wu Yi-Chen, Chang Paul A, Scholl Frank G, Drinkwater Davis C
Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232-9292, USA.
J Surg Res. 2007 May 15;139(2):203-8. doi: 10.1016/j.jss.2006.10.006. Epub 2007 Feb 9.
The radial artery (RA) has gained widespread acceptance as a conduit for coronary artery bypass. We analyze patient-based data to determine risk factors for long-term upper limb morbidities associated with RA harvest for coronary artery bypass grafting.
STUDY DESIGN/METHODS: Between April 1997 and March 2004, a total of 1030 patients underwent RA harvesting for coronary artery bypass grafting for a total of 1704 harvest sites. Patients were contacted by telephone and asked to report any ongoing severe sensory and functional motor deficits for each harvest site since surgery. Retrospective chart review was performed and preoperative risk factors were evaluated. Patient-based risk factors were evaluated for development of significant long-term local sensorimotor deficits including gender, elderly age (>70 y), diabetes, smoking, and whether the RA was harvested from the dominant hand.
Successful evaluation of 629 patients for a total of 1048 RA harvest sites was completed. The mean follow-up time was 48.3 mo (range, 2 to 86 mo). The mean age of the patients analyzed was 62.2 y. On statistical analysis, diabetics and elderly did not report significantly greater functional or sensory deficits than nondiabetics and nonelderly, respectively. There was a significantly higher incidence of sensory deficits in smokers compared with nonsmoker patients (4.2% versus 1.4%; P = 0.005) but no difference in their functional impairment was noted. Harvesting from the dominant hand did not influence the occurrence of sensory or motor functional deficits.
RA harvesting for coronary artery bypass grafting can be done with minimal serious long-term upper limb morbidity in higher risk patients. Based on our findings, harvesting of the RA from the dominant hand is not contraindicated in these patients.
桡动脉(RA)作为冠状动脉搭桥的血管 conduit 已获得广泛认可。我们分析基于患者的数据,以确定与冠状动脉搭桥术桡动脉取材相关的长期上肢疾病的危险因素。
研究设计/方法:1997年4月至2004年3月期间,共有1030例患者接受了用于冠状动脉搭桥术的桡动脉取材,共取材1704个部位。通过电话联系患者,要求他们报告自手术以来每个取材部位任何持续存在的严重感觉和功能运动缺陷。进行回顾性病历审查并评估术前危险因素。评估基于患者的危险因素与严重长期局部感觉运动缺陷的发生情况,包括性别、老年(>70岁)、糖尿病、吸烟以及桡动脉是否取自优势手。
完成了对629例患者共1048个桡动脉取材部位的成功评估。平均随访时间为48.3个月(范围为2至86个月)。所分析患者的平均年龄为62.2岁。经统计学分析,糖尿病患者和老年人分别报告的功能或感觉缺陷并不比非糖尿病患者和非老年人显著更多。与非吸烟患者相比,吸烟患者感觉缺陷的发生率显著更高(4.2%对1.4%;P = 0.005),但未观察到他们在功能损害方面存在差异。从优势手取材并未影响感觉或运动功能缺陷的发生。
对于高危患者,冠状动脉搭桥术取材桡动脉可使长期上肢严重疾病降至最低。根据我们的研究结果,这些患者从优势手取材桡动脉并无禁忌。