Gray Richard J, Forstner-Barthell Adrienne W, Pockaj Barbara A, Schild Steven E, Halyard Michele Y
Department of Surgery, Mayo Clinic, 13400 East Shea Blvd., Scottsdale, AZ 85259, USA.
Am J Surg. 2004 Aug;188(2):122-5. doi: 10.1016/j.amjsurg.2003.12.062.
Breast-conserving therapy (BCT) is reported to result in a significant rate of complications and local recurrences in patients with prior implant breast augmentation. The role of sentinel lymph node (SLN) biopsy in these patients is unknown.
Retrospective review of patients with prior breast augmentation treated with BCT or SLN biopsy.
Nineteen breast cancers were treated with BCT. Of 17 breasts undergoing adjuvant radiotherapy, 11 (64.7%) retained favorable aesthetic results. Of 9 subpectoral implants, capsular contracture developed in only 1 (11.1%). During follow-up (median 3 years), 1 local recurrence (5.3%) occurred in a patient who refused adjuvant radiotherapy and systemic therapy. Eleven patients underwent SLN biopsy with an identification rate of 100% and a false-negative rate of 0%.
Breast-conserving therapy inclusive of radiotherapy after implant breast augmentation produced acceptable cosmetic results in nearly two-thirds of patients. Sentinel lymph node mapping in the setting of prior implant augmentation was highly successful and accurate.
据报道，保乳治疗（BCT）在既往有植入式隆乳术的患者中会导致较高的并发症发生率和局部复发率。前哨淋巴结（SLN）活检在这些患者中的作用尚不清楚。
对接受BCT或SLN活检的既往隆乳患者进行回顾性研究。
19例乳腺癌患者接受了BCT治疗。在17例接受辅助放疗的乳房中，11例（64.7%）保持了良好的美学效果。在9例胸大肌下植入物中，仅1例（11.1%）发生了包膜挛缩。在随访期间（中位时间3年），1例拒绝辅助放疗和全身治疗的患者发生了局部复发（5.3%）。11例患者接受了SLN活检，识别率为100%，假阴性率为0%。
植入式隆乳术后包括放疗在内的保乳治疗在近三分之二的患者中产生了可接受的美容效果。在既往有植入式隆乳的情况下，前哨淋巴结定位非常成功且准确。
