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糖尿病患者小切口白内障手术后的角膜变化

Corneal changes after small-incision cataract surgery in patients with diabetes mellitus.

作者信息

Morikubo Soichi, Takamura Yoshihiro, Kubo Eri, Tsuzuki Shosai, Akagi Yoshio

机构信息

Division of Ophthalmology, School of Medicine, Fukui University, Fukui, Japan.

出版信息

Arch Ophthalmol. 2004 Jul;122(7):966-9. doi: 10.1001/archopht.122.7.966.

Abstract

OBJECTIVE

To evaluate functional impairment in the corneal endothelium of eyes in patients with diabetes mellitus, after small-incision cataract surgery.

METHODS

Evaluation was performed in 93 eyes in patients with type 2 diabetes mellitus (diabetic group) and 93 eyes in patients without diabetic mellitus (nondiabetic group) who underwent cataract surgery. Using a topography system, the corneal thickness in the central area was measured before surgery and 1 day, 1 week, and 1 month after surgery. Corneal endothelial cells were counted using a noncontact specular microscope.

RESULTS

No significant differences in any preoperative measures were observed between the diabetic and nondiabetic groups. The increase in corneal thickness 1 month after surgery was significantly higher in the diabetic group than in the nondiabetic group (P =.03). The corneal endothelial cell losses 1 day and 1 week after surgery were significantly higher in the diabetic group than in the nondiabetic group (after 1 day, P =.03; and after 1 week, P =.04).

CONCLUSION

Compared with nondiabetic eyes, eyes of patients with diabetes mellitus showed more damage in corneal endothelial cells due to cataract surgery and a delay in the postoperative recovery of corneal edema.

摘要

目的

评估糖尿病患者行小切口白内障手术后角膜内皮的功能损害。

方法

对93例2型糖尿病患者的患眼(糖尿病组)和93例非糖尿病患者的患眼(非糖尿病组)进行白内障手术,并进行评估。使用地形图系统,在手术前以及手术后1天、1周和1个月测量中央区角膜厚度。使用非接触式角膜内皮显微镜对角膜内皮细胞进行计数。

结果

糖尿病组和非糖尿病组术前各项测量指标均无显著差异。糖尿病组术后1个月角膜厚度增加显著高于非糖尿病组(P = 0.03)。糖尿病组术后1天和1周的角膜内皮细胞损失显著高于非糖尿病组(术后1天,P = 0.03;术后1周,P = 0.04)。

结论

与非糖尿病眼相比,糖尿病患者的眼睛因白内障手术导致角膜内皮细胞损伤更严重,且角膜水肿的术后恢复延迟。

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