Nouri Keyvan, Rivas Maria Patricia
Department of Dermatology and Cutaneous Surgery, School of Medicine, University of Miami, Miami, FL 33136, USA.
Skinmed. 2004 Jul-Aug;3(4):191-6. doi: 10.1111/j.1540-9740.2004.02458.x.
Mohs micrographic surgery is a highly effective technique for the removal of some skin cancers. The technique is founded on the idea of excision with minimal margins (sparing normal tissue) and immediate histologic examination of horizontal frozen sections of the specimen while the patient waits. By doing this, a Mohs surgeon is able to examine the margins. If residual tumor is present, subsequent excisions are performed until it is completely removed. In cases of aggressive tumors, recurrent tumors, or in which the lesions are present in high-risk anatomic locations (H-zone of the face) or functionally important areas (e.g., digits, genitals), the preferred treatment is Mohs micrographic surgery.
莫氏显微外科手术是一种切除某些皮肤癌的高效技术。该技术基于以最小切缘进行切除（保留正常组织）的理念，并在患者等待时对标本的水平冰冻切片进行即时组织学检查。通过这样做，莫氏外科医生能够检查切缘。如果存在残留肿瘤，则进行后续切除，直到肿瘤被完全切除。对于侵袭性肿瘤、复发性肿瘤，或病变位于高风险解剖部位（面部H区）或功能重要区域（如手指、生殖器）的情况，首选治疗方法是莫氏显微外科手术。
