1,3,5,7-四甲基-2,4,8-三氧杂-6-苯基-6-磷杂金刚烷的钯配合物：合成、晶体结构及其在铃木反应、Sonogashira反应和酮的α-芳基化反应中的应用
Palladium complexes of 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane: synthesis, crystal structure and use in the Suzuki and Sonogashira reactions and the alpha-arylation of ketones.
作者信息
Adjabeng George, Brenstrum Tim, Frampton Christopher S, Robertson Al J, Hillhouse John, McNulty James, Capretta Alfredo
机构信息
Department of Chemistry, McMaster University, Hamilton, Ontario, Canada L8S 4M1.
出版信息
J Org Chem. 2004 Jul 23;69(15):5082-6. doi: 10.1021/jo049474x.
Palladium complexes of 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane were prepared and characterized with Pd1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane.dba shown to be an effective catalyst for use in the Suzuki and Sonogashira reactions and the alpha-arylation of ketones. Couplings using this versatile complex proceeded in excellent yields under mild conditions.
制备了1,3,5,7-四甲基-2,4,8-三氧杂-6-苯基-6-磷杂金刚烷的钯配合物，并通过Pd1,3,5,7-四甲基-2,4,8-三氧杂-6-苯基-6-磷杂金刚烷.dba进行表征，结果表明其是用于铃木反应、 Sonogashira反应以及酮的α-芳基化反应的有效催化剂。使用这种多功能配合物进行的偶联反应在温和条件下具有优异的产率。
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