Gitelis S, Neel M D, Wilkins R M, Rao B N, Kelly C M, Yao T K
Rush Medical College, Chicago, Illinois, USA.
Chir Organi Mov. 2003 Oct-Dec;88(4):327-33.
The purpose of this paper is to review our experience with a non-invasive expandable prosthesis for skeletally immature patients following limb-salvage for malignant tumors about the knee.
MATERIALS & METHODS: Between 1998 and 2002, Repiphysis prostheses (Wright Medical Technology, Memphis, Tenn.) were implanted in 18 patients. 16 patients had at least 12 months follow-up. There were 10 males and 8 females. The diagnosis was Stage IIB osteosarcoma in all patients. Sites included femur 14, and 4 proximal tibias. The average age was 10.7 years (range 8-16); the average age for males was 12 years and females, 9 years. Fifteen of the prostheses were implanted at the time of surgical resection and the remainder was conversions of previous surgery.
Follow-up averaged 24.8 months (range 12-47). Fourteen patients have undergone a total of 58 lengthening procedures. Average expansion 38 mm per patient (range, 10-76 mm). An average of 8.5 mm per lengthening procedure. There was only one failure to lengthen. ISOLS functional scores averaged 83.5%. For those with a current functional prosthesis, the ISOLS score averaged 94%. Three patients have reached maximal expansion and converted to a conventional prosthesis. There were complications in 7 patients: 2 expandable component fractures, 1 femoral component fracture, 2 stem fractures, 1 stem loosening and 1 deep infection. Of the two expandable component fractures, 1 patient reached full expansion and was converted to an endoprosthesis. The femoral component fracture and 2 stem fractures were revised to a new prosthesis 13 months post-op and are functioning well. The 1 loose stem was revised to an APC.
The Repiphysis prosthesis utilizes energy stored in a spring that is held compressed by a locking mechanism. Controlled release of the locking mechanism via an external electromagnetic field allows for lengthening of the device. In our early experience, the functional results were excellent similar to conventional modular devices. Complications should be anticipated but are salvageable. This device allows limb salvage in pediatric patients when amputation would be otherwise chosen.
本文旨在回顾我们对一种用于膝关节恶性肿瘤保肢术后骨骼未成熟患者的非侵入性可扩张假体的应用经验。
1998年至2002年间,为18例患者植入了Repiphysis假体(Wright Medical Technology,孟菲斯,田纳西州)。16例患者接受了至少12个月的随访。其中男性10例,女性8例。所有患者的诊断均为IIB期骨肉瘤。病变部位包括14例股骨和4例胫骨近端。平均年龄为10.7岁(范围8 - 16岁);男性平均年龄为12岁,女性为9岁。15例假体在手术切除时植入,其余为既往手术的翻修。
随访平均时间为24.8个月(范围12 - 47个月)。14例患者共进行了58次延长手术。平均每位患者延长38 mm(范围10 - 76 mm)。每次延长手术平均延长8.5 mm。仅1例延长失败。国际肢体延长与重建学会(ISOLS)功能评分平均为83.5%。对于目前使用功能性假体的患者,ISOLS评分平均为94%。3例患者已达到最大扩张并转换为传统假体。7例患者出现并发症:2例可扩张部件骨折,1例股骨部件骨折,2例柄部骨折,1例柄部松动和1例深部感染。在2例可扩张部件骨折中,1例患者达到完全扩张并转换为内置假体。股骨部件骨折和2例柄部骨折在术后13个月翻修为新的假体,目前功能良好。1例松动的柄部翻修为APC假体。
Repiphysis假体利用储存在弹簧中的能量,该弹簧由锁定机构保持压缩状态。通过外部电磁场控制释放锁定机构可使装置延长。在我们的早期经验中,功能结果与传统模块化装置相似,非常出色。应预期到并发症,但可挽救。当否则会选择截肢时,该装置可实现小儿患者的肢体保全。