Swaminathan S, Paramasivan C N, Kumar S R, Mohan V, Venkatesan P
Division of HIV/AIDS, Tuberculosis Research Centre, Chennai, Tamil Nadu, India.
Int J Tuberc Lung Dis. 2004 Jul;8(7):896-8.
Diagnosis of tuberculosis is challenging, especially in human immunodeficiency virus (HIV) positive persons who may have atypical clinical and radiographic features. We report the isolation of Mycobacterium tuberculosis from sputum samples of 10 (4%) HIV-positive persons who were asymptomatic with normal chest radiographs and negative sputum smears for acid-fast bacilli. Six of them had strongly positive tuberculin reactions while four were severely immunosuppressed. Our observation highlights the utility of routine sputum culture in the diagnosis of tuberculosis in high-risk individuals.
结核病的诊断具有挑战性，尤其是在人类免疫缺陷病毒（HIV）阳性者中，他们可能具有非典型的临床和影像学特征。我们报告了从10名（4%）HIV阳性者的痰液样本中分离出结核分枝杆菌，这些人无症状，胸部X线片正常，痰涂片抗酸杆菌阴性。其中6人结核菌素反应强阳性，4人有严重免疫抑制。我们的观察结果凸显了常规痰培养在高危个体结核病诊断中的作用。
